“…The applied functional clustering based on L. monocytogenes phagosomal degradation (cluster I) and immunity (cluster II) restricted the common IFN-␥ or IL-6 transcriptional responses to seven selected genes. Four genes corresponded to cluster I, and all of them played a role in phagocytosis, such as the trafficking regulator RAB5A (4,19,22,(37)(38)(39) and the lysosomal components LAMP-2 (21), LIMP-2 (4,6,29), and the regulatory subunit A of H ϩ -ATPase (4,12,19,21,22). Three genes belong to cluster II and correspond to major components of L. monocytogenes-specific innate immunity, including the type I IFNresponse genes C3F6 and IL-6 and the type II IFN response gene STAT-1 (1,3,5,23).…”