Background:
Globally, people utilize plants as the main source of remedy to heal various
ailments. Medicinal plants have been utilized to treat ailments since the invention of modern scientific
systems of medicine. The common remedy of infectious diseases mainly depends on the inhibition capacity
of compounds or killing potential. The issue may give a clue for the development of a novel antimicrobial
agent.
Methods:
Currently, microorganisms which are resistant towards antibiotics are probably a matter of
serious concern for the overall well-being of health. At the moment, new therapeutic targets aside from
the microorganism wall-based activities are in progress. For instance, the autoinducer molecules produced
by the quorum sensing system are used to control antibiotic resistance and biofilm formation.
Results:
This therapeutic target is well-studied worldwide, however, the scientific data are not updated
and only current studies started to gain insight into its perspective as a target to struggle against infectious
diseases. Microbial resistance against antimicrobial compounds is a topic of serious concern in
recent time.
Conclusion:
Hence, this paper aims to confer a current overview of the novel compounds, quorum
sensing, quorum quenching, biofilm formation in the development of antibiotic resistance and an update
on their importance as a potential target for natural substances.