Characterization, Antifungal Susceptibility and Phenotypic Virulence Markers of Candida Isolates from Blood Stream Infection

Raj, Anshuman; Banerjee, Gopa; Venkatesh, Vimala; Gupta, Prashant; Tripathi, Shivangi; Verma, Shailendra; Verma, Nishant

doi:10.46889/jcim.2021.2304

Cited by 1 publication

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References 22 publications

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“…The results showed that some Candida isolates presented protease or phospholipase activities (Table 2). These activities have seemed in a lower percentage of samples [21,22]. hydrophobic as previously described [16].…”

Section: Identification and Characterization Of Candida Spp Isolated ...mentioning

confidence: 55%

Biofilm Formation, Virulence Factors and Antifungal Susceptibility of Candida spp. Isolated From the Oral Cavity of Diabetes Mellitus Patients

Yamauchi¹

2022

JCIM

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Background: Candida species colonize human microbiota and some conditions, such as immunosuppression or chronic illness, predispose the individual to fungal infections; among them, diabetes mellitus, a metabolic disorder frequently associated with higher rates of yeast infections. Material and Methods: The prevalence of Candida species in the oral cavity of patients with diabetes mellitus was evaluated and the carriage was compared between type 1 and type 2 diabetic groups. In addition, in vitro susceptibility to antifungals, biofilm formation, cell surface hydrophobicity, and the production of hydrolytic enzymes were tested. Results: The results demonstrated the presence of different Candida species in the oral cavity of diabetic patients; and, also showed that type 1 diabetic patients are more susceptible to Candida colonization. Almost all isolates produce virulence factors such as proteases, phospholipases, or form biofilm; and they are sensitive to fluconazole and nystatin. Conclusion: Colonization of Candida spp. oral isolates from type 1 and type 2 diabetic patients were similar; however, type 1 presented a higher colony-forming unit counting. Overall, Candida isolates from the oral cavity of diabetic patients are potential pathogens of candidiasis.

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Section: Identification and Characterization Of Candida Spp Isolated ...mentioning

confidence: 55%

Biofilm Formation, Virulence Factors and Antifungal Susceptibility of Candida spp. Isolated From the Oral Cavity of Diabetes Mellitus Patients

Yamauchi¹

2022

JCIM

View full text Add to dashboard Cite

show abstract

Characterization, Antifungal Susceptibility and Phenotypic Virulence Markers of Candida Isolates from Blood Stream Infection

Cited by 1 publication

References 22 publications

Biofilm Formation, Virulence Factors and Antifungal Susceptibility of Candida spp. Isolated From the Oral Cavity of Diabetes Mellitus Patients

Biofilm Formation, Virulence Factors and Antifungal Susceptibility of Candida spp. Isolated From the Oral Cavity of Diabetes Mellitus Patients

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