“…Especially on the metallic surface, controllable on-surface lateral manipulation of the single molecule 45 – 47 has been well established and the adsorbate can also be activated 48 by means of electric field 49 , 50 . Moreover, on the rutile TiO 2 surface, the vertical desorption of hydrogen atom 9 , 10 , 16 , 18 , 21 , reversible migration of hydrogen atom 23 , the stochastic motion of hydrogen atom induced by inelastic tunneling electrons 3 , manipulation of oxygen adatom 27 and lateral tip induced excitation of the single molecule 35 have been clarified. However, the lateral manipulation of the single hydrogen atom to the desired position on rutile TiO 2 surface has been poorly reported experimentally up to now 10 , although it could provide an efficient means of the arrangement of the on-surface water splitting reactions, dissociation dynamics, which critically control the efficiency of heterogeneous catalytic reactions on this surface 1 – 23 .…”