Characterization and quality assessment of binding properties of malachite green molecularly imprinted polymers prepared by precipitation polymerization in acetonitrile

Preparation of Thermosensitive Hollow Imprinted Microspheres via Combining Distillation Precipitation Polymerization and Thiol‐ene Click Chemistry

“…From the spectrometry we can count out the binding constant and complex ratio between AM (host) and S-IBF (guest). According to the literature, [31] when host-to-guest ratio is 2∶1, a linear curve can be drawn The procedures of synthesis of hairy hollow imprinted microspheres (MIPs(AM-co-EGDMA)-g-PNIPAM) with S-IBF molecular imprinted shell and temperature-responsive PNIPAM brushes are illustrated in Scheme 1. There are four stages: (I) the silica-3-(trimethoxysilyl)propyl methacrylate (SiO 2 -MPS) template microspheres were synthesized via the modified Stöber method; (II) SiO 2 @MIPs microspheres were synthesized by distillation precipitation polymerization of acrylamide (AM), in the presence of ethylene glycol dimethacrylate (EGDMA, as a cross-linking agent), using the SiO 2 -MPS as template microspheres; (III) through thiol-ene click chemistry, the SiO 2 @MIPs microspheres were modified by PNIPAM-SH which were synthesized via RAFT polymerization; (IV) through extraction, the templates (S-IBF) in the imprinted shell were removed.…”

Preparation of new molecularly imprinted quartz crystal microbalance hybride sensor system for 8-hydroxy-2′-deoxyguanosine determination

“…The binding interaction and equilibrium information between the imprinted polymer and 8-OHdG template can be obtained by Scathard analysis (Fig. 4) and a tool was already applied [35,36]. This analysis employs Eq.…”

Isotherm Studies of Pyrogallol-imprinted Polymers via Precipitation Polymerization

“…There are several principles in the process of molecular imprinting, which are as follows: (1) formation of specific complex from noncovalent bond of interactions between the template molecule(s) and the functional monomer in a polar or aprotic solvent, obtained by assembling the functional monomer around the template molecule before the polymerization process; (2) in the present of cross-linker and initiator, a rigid and porous copolymer must be obtained; and (3) the distinct cavities remain complementary to the target template molecule in size, shape and functionality after the removal of the target molecule (Yan et al, 2007;Yusof et al, 2010).…”

“…Due to their molecular recognition capability, MIPs have captured the imagination of many and their use is encouraged in numerous application areas such as in: solid-phase extraction (Tamayo et al, 2007;Lanza & Sellergren, 2001;Andersson & Schweitz, 2003); sensor (Liu et al, 2012;Uzun & Turner, 2016;Haupt & Mosbach, 2006); chromatography (Yan et al, 2007); amino acid derivatives (Scorrano et al, 2011); and drugs (Sellergren & Allender, 2005;Lulinski, 2013). Not only easy and low-cost, the synthesis of MIPs also produced polymers that are stable, versatile and resistant to a wide range of pH, solvents and temperature (Cormack & Elorza, 2004).…”