Characterization and in vivo assay of chitosan alginate microencapsulation to deliver the combination of HBcAg and HBsAg as a hepatitis B oral vaccine candidate
Abstract:Chronic hepatitis B infection is one of main factors of cirrhosis primary cause, which can develop into hepatocellular carcinoma. Medically, there are various disadvantages associated with administering hepatitis B vaccine through injection, include pain, reduced patient compliance, higher production costs, and inadequate mass vaccination. Therefore, it is necessary to develop an oral vaccine. This study aims to develop and characterize oral vaccine through combination of Hepatitis B Surface Antigen (HBsAg) an… Show more
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