Abstract:Background: Minimal change disease (MCD) is one of the most common causes of primary nephrotic syndrome with high morbidity. This study aimed to explore the typical alterations of gut microbiota in MCD and establish a non-invasive classifier using key gut microbiome. We also aimed to evaluate the therapeutic efficiency of gut microbiota intervention in MCD through animal experiments.Methods: A total of 222 stool samples were collected from MCD patients and healthy controls at the First Affiliated Hospital of Z… Show more
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