Characterization and clinical outcome of patients with possible infective endocarditis

Time-sensitive predictors of embolism in patients with left-sided endocarditis: Cohort study

“…We found that increased rates of any EE were associated with definite IE according to Duke criteria [30, 35] and absence of malignancy [17], but not with coagulase-negative staphylococcal or viridans group streptococcal infections [14, 17, 24], in keeping with prior reports. We did not observe an association between EEs and Staphylococcus aureus infection despite previous observations [6, 12–17].…”

“…We investigated 116 patients with definite or probable IE to identify clinical, microbiological, and echocardiographic characteristics associated with EEs. EEs occurred in 37% of patients, congruent with previously reported rates of 18–44% [17, 24, 30, 31]. The large majority of EEs occurred before or on the day of hospital admission, thereby precipitating medical contact.…”

“…The small number of EEs after echocardiography limited statistical power. Inclusion of a high proportion of probable IE patients (31% compared to 7–11% seen in large multicentre studies [9, 17, 30]), of which a majority had no echocardiographic findings, may have also diluted the observed associations. Finally, the performance of cardiac surgery may have reduced the risk of a subsequent EE.…”

Clinical and echocardiographic predictors of embolism in infective endocarditis: systematic review and meta-analysis

“…Citations excluded after full-text screening are listed in the Supplementary material. All studies were of cohort design; 37 were retrospective [3,5,6,13,22e25,27e30,32,34e39,41,42,45e60] and ten were prospective [8,11,12,21,26,31,33,40,43,44]. Studies were primarily in English (n ¼ 41) [3,5,6,8,11e13,21e44,48e51,54e57,59,60], with additional studies in French [58], Spanish [46], German [47,53], Czech [52] and Chinese [45].…”

Neutrophil­to­lymphocyte ratio: A novel and simple prognostic marker for infective endocarditis

“…Infective endocarditis (IE) is a life-threatining infectious disease characterized by high morbidity and mortality [1,2]. Leukocytes play a main role in infectious diseases.…”