Characterization and Antimicrobial Activity of Nanocurcumin and Curcumin

Shailendiran, D.; Pawar, Nisha; Chanchal, A.; Pandey, Raju; Bohidar, H. B.; Verma, Anita

doi:10.1109/nstsi.2011.6111984

Cited by 14 publications

(8 citation statements)

References 8 publications

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“…The study of nanocurcumin as a nanoparticle of curcumin with the size of 2–40 nm processed by a wet-milling technique, showed curcumin to be more freely dispersible in water leading to more significant antimicrobial activity against Staph. aureus, E. coli, P. aeruginosa, B. subtilis, and two fungi of P. notatum and A. niger due to reduced particle size and enhanced bioavailability [ 95 , 96 ]. However, nanocurcumin demonstrated more noteworthy activity against Gram-positive bacteria rather than Gram-negatives [ 95 ].…”

Section: Enhancing the Bioavailability And Solubility Of Curcumin mentioning

confidence: 99%

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

Moghadamtousi

Kadir

Hassandarvish

et al. 2014

BioMed Research International

880

608

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Curcuma longa L. (Zingiberaceae family) and its polyphenolic compound curcumin have been subjected to a variety of antimicrobial investigations due to extensive traditional uses and low side effects. Antimicrobial activities for curcumin and rhizome extract of C. longa against different bacteria, viruses, fungi, and parasites have been reported. The promising results for antimicrobial activity of curcumin made it a good candidate to enhance the inhibitory effect of existing antimicrobial agents through synergism. Indeed, different investigations have been done to increase the antimicrobial activity of curcumin, including synthesis of different chemical derivatives to increase its water solubility as well ass cell up take of curcumin. This review aims to summarize previous antimicrobial studies of curcumin towards its application in the future studies as a natural antimicrobial agent.

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Section: Enhancing the Bioavailability And Solubility Of Curcumin mentioning

confidence: 99%

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

Moghadamtousi

Kadir

Hassandarvish

et al. 2014

BioMed Research International

880

608

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“…[52] Stable and different shapes of nanoparticles of curcumin in ethanol/ water solutions prepared by the method of sonication-assisted solvent worsening, and this nano curcumin showed a better balance of solubility and bioavailability and promising in vitro antimicrobial activity compared with curcumin. [53] Figure 11. Curcumin esters with succinic acid derivatives.…”

Section: Nano Curcuminsmentioning

confidence: 99%

Curcumin – Bioavailability Enhancement by Prodrug Approach and Novel Formulations

Chelimela,

Alavala,

Satla

2024

Chemistry & Biodiversity

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Curcumin, is a diverse natural pharmacological agent involved in various signal transduction mechanisms. Therapeutically, this potent molecule facing different challenges and issues related to low bioavailability due to its poor aqueous solubility, less permeability, faster elimination and clearance. Experts in synthetic chemistry and pharmaceuticals are continuously sparing their efforts to overcome these pharmacokinetic challenges by using different structural modification strategies and developing novel drug delivery systems. In this mini‐review article, we are focusing on different possible routes like conjugation with biomolecules, natural polymers, synthetic polymers, natural products, metal conjugates and co‐administration with natural metabolic inhibitors and preparation of modified formulations such as micelles, microemulsions, liposomes, complexes with phospholipids, micro and nanoemulsions, solid lipid nanoparticles, nano lipid carriers, biopolymer nanoparticles and microgels to improve the pharmacokinetic properties of the curcumin without altering its pharmacodynamics activity. Hope this review helps to understand the problems associated with curcumin and different strategies to improve the pharmacokinetic profile of the curcumin.

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“…aureus, E. coli, P. aeruginosa, B. subtilis and two fungi of P. notatum and A. niger due to reduced particle size and enhanced bioavailability. 17,18 However, nanocurcumin demonstrated more noteworthy activity against Gram-positive bacteria rather than Gram negatives. 17 In another study to improve the stability and solubility of curcumin, microencapsulation process was investigated.…”

Section: Pregnancy and Lactationmentioning

confidence: 99%

Curcumin- A Boon for Oral Health

Pramod¹,

Reddy²,

Raj³

et al. 2018

jemds

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BACKGROUND Turmeric is a spice derived from the rhizomes of Curcuma longa, which is a member of the ginger family (Zingiberaceae). In addition to its use as a spice and pigment, Turmeric has been used for centuries in herbal medicines for the treatment of a variety of disorders such as rheumatism, diabetic ulcers, anorexia, cough and sinusitis. Curcumin (Diferuloylmethane) is the main active constituent present in turmeric, responsible for its yellow colour. It has been shown to possess significant anti-inflammatory, antioxidant, anti-carcinogenic, anti-mutagenic, anticoagulant and anti-infective effects.

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Characterization and Antimicrobial Activity of Nanocurcumin and Curcumin

Cited by 14 publications

References 8 publications

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

Curcumin – Bioavailability Enhancement by Prodrug Approach and Novel Formulations

Curcumin- A Boon for Oral Health

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