Characterization and Antifungal Susceptibility Profile of Candida Species Isolated from Candiduria Cases in a Tertiary Care Hospital, Kolkata

Ghosh, Reena Ray; Haldar, Piyali; Chatterjee, Mitali

doi:10.20546/ijcmas.2019.806.133

Cited by 1 publication

(1 citation statement)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other procedures, such as Gram stain, germ tube test, and culture on chromogenic Candida agar were performed after direct microscopic examinations and sub-culturing on SDA [21]. The clinical isolates were identified by classical methods and were compared to standard strains, as the main target of study was to evaluate the anticandidal activity of extracted biomolecules against diverse Candida spp.…”

Section: Isolation and Identification Of Clinical Isolatesmentioning

confidence: 99%

Exploring the Antifungal Activity and Action of Saussurea costus Root Extracts against Candida albicans and Non-albicans Species

et al. 2022

View full text Add to dashboard Cite

The isolation and assessment of the active constituents in polar and non-polar crude extracts of Saussurea costus roots as antifungal agents, against Candida albicans and non-C. albicans (NAC) species, was the aim of this current investigation. The SEM “Scanning electron microscopy” imaging provided potential action modes of n-hexane extract (nhhE) toward Candida spp., whereas the TLC-DB “Thin layer chromatography-direct bioautography” was employed for detecting the anticandidal compounds. nhhE had the greatest biocidal activity against all strains and clinical isolates of Candida spp. with maximum zones of inhibition. SEM revealed the occurrence of irregular, dense inclusions of C. albicans cell walls after treatment with nhhE for 12 h. Complete morphological distortions with lysed membranes and deterioration signs appeared in most treated cells of C. parapsilosis. The most effectual compound with anticandidal activity was isolated using TLC-BD and identified as sesquiterpene by GC/MS analysis. The infra-red analysis revealed the presence of lactone ring stretching vibrations at 1766.72 cm−1. The anticandidal activity of nhhE of S. costus roots was confirmed from the results, and the treated cotton fabrics with nhhE of S. costus possessed observable activity against C. albicans. Data could recommend the practical usage of S. costus extracts, particularly nhhE, as influential natural bioactive sources for combating pathogenic Candida spp.

show abstract

Section: Isolation and Identification Of Clinical Isolatesmentioning

confidence: 99%

Exploring the Antifungal Activity and Action of Saussurea costus Root Extracts against Candida albicans and Non-albicans Species

et al. 2022

View full text Add to dashboard Cite

show abstract

Characterization and Antifungal Susceptibility Profile of Candida Species Isolated from Candiduria Cases in a Tertiary Care Hospital, Kolkata

Abstract: Fungal infections of the urinary tract encompass a broad variety of fungi, However, the overwhelming majority of fungal infections of the urinary tract are caused by Candida species. Candida species account for almost 10-15% nosocomial UTI 1 . The

Cited by 1 publication

References 11 publications

Exploring the Antifungal Activity and Action of Saussurea costus Root Extracts against Candida albicans and Non-albicans Species

Exploring the Antifungal Activity and Action of Saussurea costus Root Extracts against Candida albicans and Non-albicans Species

Contact Info

Product

Resources

About