Characterization and Abundance of Plasmid-Dependent Alphatectivirus Bacteriophages
Boris Parra,
Veronika T. Lutz,
Lone Brøndsted
et al.
Abstract:Antimicrobial resistance (AMR) is a major public health threat, exacerbated by the ability of bacteria to rapidly disseminate antimicrobial resistance genes (ARG). Since conjugative plasmids of the incompatibility group P (IncP) are ubiquitous mobile genetic elements that often carry ARG and are broad-host-range, they are important targets to prevent the dissemination of AMR. Plasmid-dependent phages infect plasmid-carrying bacteria by recognizing components of the conjugative secretion system as receptors. We… Show more
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