Characteristics of strong-acid cation exchangers 1. Optimization of regeneration

Sauer, Charles A.

doi:10.1016/0011-9164(84)87004-6

Cited by 3 publications

(2 citation statements)

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“…The medication history estimator was applied to pharmacy dispensing data to reconstruct patients' historical medication treatment episodes. [20] The medication history estimator implemented workflows to clean and structure data and to calculate treatment episodes (i.e., patiromer treatment courses) from outpatient dispensing data. Rules were implemented to correct errors in the data (e.g., duplicates, fills that were not released, improbable units and days' supply) and standardize the total mg dispensed with each dispensing event.…”

Section: Patiromer Utilizationmentioning

confidence: 99%

Real-world evaluation of patiromer utilization and its effects on serum potassium in veterans with end stage kidney disease

et al. 2022

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Hyperkalemia (serum potassium [K+] ≥5.1) is life-threatening in patients diagnosed with end stage kidney disease (ESKD). Patiromer is approved for the treatment of hyperkalemia, although its role in hyperkalemic patients with ESKD is not well understood. This study describes real-world patiromer utilization in an ESKD population and its corresponding association with serum K+ level changes. The study population was comprised of US veterans with an outpatient dispensing of patiromer and 2 or more International Classification of Diseases diagnostic codes for ESKD. A treatment course of patiromer was defined by serial dispensing events without a 30-day gap. Patiromer utilization was described by duration, average dose, persistence, and proportion of days covered during patiromer course. Mean serum K+ values were described for baseline and 3 follow-up intervals during the 180-day follow-up period. There were 458 patients with ESKD included in the study. On average, patients had 1.24 (95% CI: 1.20–1.29) patiromer courses. Half of the population discontinued their first patiromer course within 30 days, while approximately 10% of patients remained persistent at the end of the 180-day period and 102 (22.3%) patients started a second course during the 180-day follow up period. Average serum K+ concentrations during baseline and the 3 evaluation intervals during the 180-day follow-up were 5.91 mEq/L (5.85–5.97), 4.94 mEq/L (4.86–5.03), 4.89 mEq/L (4.8–4.98) and 4.88 mEq/L (4.8–4.96). Few patients remained persistent on their initial course of patiromer at the end of follow-up, but approximately 20% of patients initiated a second treatment episode after a 30-day gap in treatment during the 180-day follow-up period. Nonetheless, average serum K+ in ESKD patients were sustainably reduced by approximately 1 mEq/L during follow-up.

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Section: Patiromer Utilizationmentioning

confidence: 99%

Real-world evaluation of patiromer utilization and its effects on serum potassium in veterans with end stage kidney disease

et al. 2022

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“…For the common regeneration method, the concentration and purity of the regenerant are the two factors influencing the degree of regeneration [18]. To obtain the ideal degree of regeneration, the high concentration of the regeneration solution (HCl solution) was adopted.…”

Section: Regeneration Of the Exhausted Al Form Resinsmentioning

confidence: 99%

A new regeneration approach to cation resins with aluminum salts: application of desalination by its mixed bed

Liu

Zhu

2010

Front. Environ. Sci. Eng.

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A novel method for the regeneration of cation exchange resins by aluminum (Al) salts was investigated in order to improve the regeneration efficiency of resins and reduce the dosage of regenerant. The influences of Al 3+ concentration and the pH of regeneration solution on resin transformation had been studied. The desalination experiments were carried out to evaluate the characteristics of the Al form resins. Experimental results showed that the regeneration rate of resins was strictly dependent on Al 3+ concentration and the pH of the solution. Compared to the conventional regeneration method, the Al form mixed bed exhibited the same desalination capability as the H form mixed bed (MB), and the total organic carbon (TOC) removal was up to 90%, clearly higher than that of the H form. Al salt solution could be utilized repeatedly to regenerate Al form resins.

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Minimizing the environmental impact of the regeneration process of an ion exchange bed charged with transition metals

Valverde

Lucas

Carmona

et al. 2006

Separation and Purification Technology

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Characteristics of strong-acid cation exchangers 1. Optimization of regeneration

Cited by 3 publications

References 1 publication

Real-world evaluation of patiromer utilization and its effects on serum potassium in veterans with end stage kidney disease

Real-world evaluation of patiromer utilization and its effects on serum potassium in veterans with end stage kidney disease

A new regeneration approach to cation resins with aluminum salts: application of desalination by its mixed bed

Minimizing the environmental impact of the regeneration process of an ion exchange bed charged with transition metals

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