Characteristics of serum lipid levels in patients with hypertension: a hospital-based retrospective descriptive study

Abstract

BackgroundDyslipidaemia is different among patients with hypertension in different populations. The serum lipid profiles among Hakka patients with hypertension in southern China are still unclear.Methods35 448 patients with hypertension were enrolled in this study from January 2016 to October 2020, and their serum lipids were analysed.ResultsLow high-density lipoprotein-cholesterol (HDL-C) (29.9%) accounted for the highest proportion in dyslipidaemia, followed by high triglyceride (TG) (20.7%), high total cholesterol (TC) (14.0%) and high low-density lipoprotein-cholesterol (LDL-C) (7.9%) in all subjects. The largest proportion of dyslipidaemia types was independent low HDL-C (12.7%). The proportion of low HDL-C was 15.5% in non-elderly men, 6.4% in non-elderly women, 16.7% in elderly men and 8.5% in elderly women, respectively. The largest proportion of dyslipidaemia types was independent high TG in non-elderly female patients (13.7%) and elderly patients (8.9%). The results showed that higher LDL-C, TC and TG levels in non-elderly patients than elderly patients. TG, TC and LDL-C levels decreasing with the increasing age, the differences were statistically significant. The levels of TG, TC, HDL-C and LDL-C in women were higher than in men among various age groups. Homocysteine level was increasing with increasing age.ConclusionsSerum lipid levels varied in different groups according to age and sex in patients with hypertension. Dyslipidaemia is more common in non-elderly patients than elderly. TG, TC and LDL-C levels were higher in female patients than male.

Prevalence of and factors associated with uncontrolled hypertension among patients with early chronic kidney disease attending tertiary hospitals in Dodoma, Tanzania: a cross-sectional study

“…Tanzania and other third world countries are undergoing epidemiological transition associated with urbanisation and sedentary lifestyle with increasing overweight/obesity, dyslipidaemia, hypertension, diabetes, CVDs and CKD 27 30 46. In this study, the prevalence of dyslipidaemia among patients with uncontrolled hypertension was 60.0%, similar to the findings from previous studies where the prevalence increased with uncontrolled hypertension and across the CKD stages from 1 to 5 50 51. The prevalence of dyslipidaemia among patients with uncontrolled hypertension and CKD is usually high 52 53.…”

“…27 30 46 In this study, the prevalence of dyslipidaemia among patients with uncontrolled hypertension was 60.0%, similar to the findings from previous studies where the prevalence increased with uncontrolled hypertension and across the CKD stages from 1 to 5. 50 51 The prevalence of dyslipidaemia among patients with uncontrolled hypertension and CKD is usually high. 52 53 Dyslipidaemia is associated with rapid CKD progression, and increased morbidity and mortality from CVD.…”

Lipid Profile Alterations and Predisposing factors associated with Cardiovascular Diseases at Kibagabaga District Hospital, Rwanda: A cross sectional study

“…The study also reported a significant difference in LDL-C levels among individuals of different ages, with the exception of those aged 50-59 years compared to those aged <50 years, where there was no difference in the mean; however, the mean difference was statistically significant in all age groups in females and males except for those aged <50 years. High levels of HDL-C were observed in individuals aged 50-59 years, 60-69 years, 80-89 years, and ≥90 years compared to those aged <50 years, and there were statistically significant differences in HDL-C levels among various age groups when comparing females with males, and HDL-C levels among females of various ages were greater than those among males [51]. In adults living in the southeastern coastal region of China, the prevalence of dyslipidemia and the risk of CVDs were studied, and the overall prevalence of dyslipidemia was 56.8% among older adults.…”

The role of serum lipid profile in the pathogenesis of arterial hypertension

“…Patients with hypertension exhibited serum lipid levels that varied depending on age and sex, with non-elderly individuals being more prone to dyslipidemia compared to the elderly. Female patients exhibited higher TG, LDL-C, and TC levels compared to males (24).…”

“…Oxidized low-density lipoprotein (ox-LDL) is a crucial component in the impact of hyperlipidemia on vascular endothelial damage. Ox-LDL primarily induces damage and dysfunction in the endothelium, favoring the development of atherosclerosis (24,28). The process of LDL oxidation is not clearly defined.…”