Characteristics of Scoliosis in Mice Induced by Chondrocyte-specific Inactivation of L-type Amino Acid Transporter 1
Makoto Handa,
Satoru Demura,
Noriaki Yokogawa
et al.
Abstract:Study Design.
A mouse study of the Slc7a5 gene using conditional knockout to assess the effects of its inactivation on spinal deformity.
Objectives.
This study aimed to investigate whether the mice with scoliosis (induced by chondrocyte-specific inactivation of L-type amino acid transporter 1 [LAT1]) show a developmental process similar to that of pediatric scoliosis and to examine the relationship between reduced bone mineral density (BMD) and scoliosi… Show more
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