Characteristics of post donation information donors and comparison with appropriately deferred donors

Abstract

No previous studies have described the characteristics of PDI donors or examined how PDI donors are different from AD donors for the same deferral reasons. We found that PDIs are more likely in older, male donors with higher levels of education when compared to AD donors.

Understanding noncompliance with selective donor deferral criteria for high‐risk behaviors in Australian blood donors

“…While our study did not show any significant association between failure to read predonation background material and noncompliance, we recognize the important role of donor education in improving risk disclosure as reported by researchers from other countries such as the United States . Effective delivery of predonation education material, using interactive ways of delivering information, and repeating important information in multiple formats are a few of the suggested measures for improving communication with potential donors, which is expected to improve compliance to the screening process overall.…”

“…Finally, this study only included some of the high‐risk deferrals while noncompliance with other criteria (such as travel or incarceration) is not uncommon. According to a US study, the largest proportion of donors with postdonation information were those who did not disclose travel‐related (58.7%) information followed by medical (20.3%), high‐risk sexual behavior (10%), blood or disease exposure (6.22%), and high‐risk nonsexual behavior (includes IDU and incarceration; 4.76%) …”

“…The majority focused on permanent deferral for male‐to‐male sex with a range of noncompliance of 0.8% to 2.3% among male donors . A few studies assessed other high‐risk nonsexual behaviors such as injecting drug use (IDU) . However, there is a paucity of data concerning noncompliance with high‐risk heterosexual deferrals (e.g., sex workers and their sexual contacts).…”

Blood Component Recalls and Market Withdrawals: Frequency, Reasons, and Management in the United States

“…As we have seen, most of the currently estimated 0.4% of blood components discovered to be noncompliant after release come from donors who should have been deferred but were not. Donors who generated BPDs with postdonation information are more likely older, male, and more educated than deferred donors [72]. Table 7 lists several problems that have been identified with donor screening and deferral.…”

The National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Studies (Retrovirus Epidemiology Donor Study and Retrovirus Epidemiology Donor Study-II): Twenty Years of Research to Advance Blood Product Safety and Availability

“…Comparing appropriately deferred donors and PDI donors within the same broad deferral categories (travel, medical, blood disease or exposure, and high-risk–sexual and high-risk–nonsexual behaviors) it was found that PDI donors were more likely to be older, more educated, and male. 131 In a separate qualitative study, telephone interviews were conducted with appropriately deferred donors, PDI donors, and accepted donors just after their donation attempt or successful donation, respectively. Based on the interviews it was theorized that donors may need assistance from blood center staff on remembering dates for deferrable activities or, in some cases, in understanding specific items on the health history questionnaire.…”