Characteristics Of Persons With Spinal Cord Injury As Documented By Use Of An Interactive Data System

Js, Walter; Sacks, Jerome; Othman, Raslan; Scianna, Joseph M.; Nemchausky, Bernard A.; Chintam, Rani; Anfinsen, L

doi:10.1080/10790268.2000.11753534

Cited by 3 publications

(4 citation statements)

References 19 publications

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“…In four cases, there were either two or three publications on apparently the same or very similar population/dataset: (1) Walter et al. (2000, 2002); (2) Jensen et al. (2005, 2007), Raichle et al.…”

Section: Resultsmentioning

confidence: 99%

Pain prevalence and its determinants after spinal cord injury: A systematic review

Gorp

Kessels

Joosten

et al. 2014

European Journal of Pain

119

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Pain prevalence studies are important as they illustrate the magnitude of pain problems in a certain patient population, such as patients living with a spinal cord injury (SCI). Strikingly, reported pain prevalence rates in SCI patients are found to vary greatly, while determinants for the differences between pain prevalence reports remain unclear. We here aim to identify determinants for the differences (heterogeneity) in pain prevalence reports through a systematic review of all SCI pain prevalence reporting studies. Literature search was done using Medline, Cumulative Index to Nursing and Allied Health Literature, ISI Web of Knowledge and Embase. Data abstraction was performed while blinded and was followed by meta-(regression)-analyses. We identified 82 studies. Study design-related determinants of SCI pain prevalence reports were pain definition strictness (mild, moderate or high), primary study goal (pain study or not), data source (retrospective or not), and in a limited number of cases response/attrition rates. While correcting for these items, population characteristics correlating with pain prevalence rates were both proportion of patients with a depression and average time after injury (positive correlations). Between-study heterogeneity may remain even after the identification/correction of above-mentioned causes of heterogeneity.Pain after SCI does seem to relate to the duration of the injury and depression, yet major causes of bias in reported pain prevalence are found to be related to the primary study goal (pain study or not), choice of pain definition and the use of retrospective data.

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Section: Resultsmentioning

confidence: 99%

Pain prevalence and its determinants after spinal cord injury: A systematic review

Gorp

Kessels

Joosten

et al. 2014

European Journal of Pain

119

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“…The orgasm is thought to inhibit spinal reflexes. Also, the inhibitory effects may be longer lasting than those reported for neuromodulation [13,14]. Thus, vibratory therapy should be considered when bladder inhibition therapy is being sought for individuals with SCI.…”

Section: Discussionmentioning

confidence: 99%

“…The first study was a national survey of use of standing wheelchairs and standing devices [2,3] and was followed by a database study in an SCI clinic. [15][16][17]. Users of regular standing reported a wide range of benefits including improved quality of life and spasticity relief.…”

Section: Discussionmentioning

confidence: 99%

A Survey of SCI Individuals Who Use a Ferti CareR Personal Vibrator: Reproduction, Bladder Program, Spasticity and Quality of Life

2010

IJU

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Introduction: For individuals with spinal cord injury, the Ferti Care R Personal vibrator can be applied to the genitalia for reproductive health and orgasm. In addition, reports of vibratory effects on spasticity and bladder inhibition have been reported. However, there is no reported owner survey for the devices home-use, either benefits or problems.Methods: 122 SCI individuals (69% response rate) who had been using the device for 2 to more than 4 years completed a mailed survey which included a wide range of device related questions.Results: Respondents were primarily males (90%) between 20 and 60 years old. Seventy-two percent had cervical or upper thoracic injury and 56% had complete injuries; 91% are using the device currently, but 48% have periods of nonuse. They were using it for orgasm (ejaculation, 84%) and sexual activity (68%). Most respondents also perceived improvement since starting to use the device in health areas including: overall health (70%), quality of life (96%), leg spasticity (80%), sleeping (65%), decreased urinary incontinence episodes (71%) and decreased rate of urinary tract infections (57%). Help with having 22 children was reported by 14 owners. Problems with use included few or no erections (77%), skin problems (13%), and needing medication for high blood pressure during use (10%). Conclusions: This is the first survey of use and nonuse of a vibrator by individuals with SCI. High percentages of respondents reported benefit in areas of sexual health, quality of life, spasticity relief and bladder inhibition. Problems with use were limited. Thus, vibratory therapy should be considered further in SCI rehabilitation programs as well as for continued outcomes research.

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“…In four cases, there were either two or three publications on apparently the same or very similar population/dataset: 1) Walter et al (Walter 2000, Walter 2002, 2) Jensen et al and Raichle et al (Jensen 2005, Raichle 2007, 3) Gerhart et al andJohnson et al (Gerhart 1992, Johnson 1998), and 4) Klotz et al andVille et al (Klotz 2002, Ville 2001). The study results from the two publications were joined together for this review, which resulted in a total amount of 82 samples (flow diagram: see Fig.…”

Section: Figure Ii-1: Flow Diagram Summarizing Systematic Search and Study Inclusionmentioning

confidence: 99%

Translational research on spinal cord injury and cell-based therapies : a focus on pain and sensorimotor disturbances

Gorp¹

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People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website.• The final author version and the galley proof are versions of the publication after peer review.• The final published version features the final layout of the paper including the volume, issue and page numbers. Link to publication General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal.(dorsal hemisection T13-L1) of adult rats has only marginal effects on severed axons (i.e. corticospinal axons were found more closely to the lesion site, but not not cross the lesion). This lack of axon regeneration could, however, be related to the characteristics of the scaffold material; the break-down products of poly(D,L)-lactide are acidic which may be detrimental for good integration of the scaffold within the spinal cord lesion; also the matrices used only supported seeding OEC on the matrix surface leaving the grafted cells directly exposed to the toxic environment of the injured spinal cord (Deumens 2006a). (Human) neural stem cellsAnother promising cell-based therapy for repair of the injured spinal cord involves (human) neural stem cells. These cells have the potential to provide cell-replacement for both neurons and glia.However, it has been -and still can be-a main problem that neural stem cells tend to mostly differentiate into astrocytes, which, in some cases, can support neuronal hyperexcitability (Hofstetter 2005, Martino 2006, Setoguchi 2004). Neuronal and oligodendroglia differentiation would certainly lead to better therapeutic effects of neural stem cell treatment (Abematsu 2010, Cummings 2005, Keirstead 2005). Neurons derived from neural stem cells are able to fully integrate into the host circuitry and their oligodendrocytes effectively remyelinate axons (Englund 2002, Keirstead 2005). Human fetal spinal cord derived neural stem cells (HSSC) grown in a monolayer, have shown to give rise to neurons, astrocytes, and oligodendrocytes in a rodent SCI model (Yan 2007). Furthermore, these HSSC were shown to be able to reduce spasticity (and improve locomotor function) after intraspinal grafting in a rodent SCI model of spasticity, which was attributed to their differentiation in inhibitory (γ-aminobutyric acid-ergic (GABA) and glycinergic neurons (Cizkova 2007). Lack of inhibition might be an important mechanism for neuronal hyperexcitability underlying pain and spasticity after SCI (Gwak 2011b). Furthermore, by impr...

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Characteristics Of Persons With Spinal Cord Injury As Documented By Use Of An Interactive Data System

Cited by 3 publications

References 19 publications

Pain prevalence and its determinants after spinal cord injury: A systematic review

Pain prevalence and its determinants after spinal cord injury: A systematic review

A Survey of SCI Individuals Who Use a Ferti CareR Personal Vibrator: Reproduction, Bladder Program, Spasticity and Quality of Life

Translational research on spinal cord injury and cell-based therapies : a focus on pain and sensorimotor disturbances

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