Characteristics of Pediatric Scrub Typhus Eschar in South Indian Children

Babu, Thirunavukkarasu Arun; Vijayadevagaran, Vijayasankar; Ananthakrishnan, S

doi:10.1111/pde.13048

Cited by 13 publications

(8 citation statements)

References 9 publications

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“…There is a different pattern in female patients, whose anterior chest, head and neck are the most prevalent areas [ 13 , 14 ]. Eschars are also commonly present in the axillae of children in addition to the sites mentioned above [ 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

A review of the global epidemiology of scrub typhus

et al. 2017

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Scrub typhus is a serious public health problem in the Asia-Pacific area. It threatens one billion people globally, and causes illness in one million people each year. Caused by Orientia tsutsugamushi, scrub typhus can result in severe multiorgan failure with a case fatality rate up to 70% without appropriate treatment. The antigenic heterogeneity of O. tsutsugamushi precludes generic immunity and allows reinfection. As a neglected disease, there is still a large gap in our knowledge of the disease, as evidenced by the sporadic epidemiologic data and other related public health information regarding scrub typhus in its endemic areas. Our objective is to provide a systematic analysis of current epidemiology, prevention and control of scrub typhus in its long-standing endemic areas and recently recognized foci of infection.

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Section: Introductionmentioning

confidence: 99%

A review of the global epidemiology of scrub typhus

et al. 2017

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“…9 Babu et al, in their prospective study found only 34.6% of serologically confirmed scrub typhus to have eschar. 10 Absence of eschar could be secondary to previous exposure to ricketssial antigen and variation in cutaneous immune response and that could be possible reason for absence of eschar in majority of our study children.…”

Section: Discussionmentioning

confidence: 78%

Clinical and laboratory predictors to differentiate severe dengue from scrub typhus in children

Elangovan

Rajesh

2019

Int J Contemp Pediatr

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Background: Objective of study was to compare the clinical features and laboratory parameters at admission and differentiate severe dengue from scrub typhus in children.Methods: Retrospective analysis of case records and comparison of clinical and laboratory parameters at admission of all children with a diagnosis of severe dengue and scrub typhus was done.Results: A total of 72 children were included (severe dengue =40; scrub typhus =32) during the study period. The mean (SD) age of children with severe dengue and scrub typhus was 7.9(3.8) and 11.8(5.8) years, respectively. Majority of children with severe dengue presented with hypotension, 21(52.5%) vs 3(9.4%) in scrub typhus. Children with severe dengue had a relatively low ANC (2.6±1.97x103/mm3 vs 3.9±2.06x103/mm3), low platelet count (50.23±35.55x103/mm3 vs 140±95.0x103/mm3) and low mean ESR at 1hour (8.1±6.82mm vs 33.88±13.79mm) than scrub typhus.Conclusions: Compared to scrub typhus, severe dengue was significantly associated with hypotension, lower ANC, ESR and platelets.

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“…Lack of pain and hidden anatomical locations make it difficult to spot an eschar. Enlarged and tender regional lymph nodes may suggest the possibility of an occult eschar in the draining areas 4,5 …”

Section: Discussionmentioning

confidence: 99%