Characteristics of patients with plaque psoriasis who have discordance between Psoriasis Area Severity Index and dermatology life quality index scores

Bretèque, M. Amy de la; Beauchet, Alain; Quiles‐Tsimaratos, N.; Estève, É.; Guyadec, T. Le; Ruer‐Mulard, M.; Maccari, F.; Réguiai, Z.; Girard, Christian; Bastien, M.; Avenel-Audran, M.; Pauwels, C.; Bouilly-Auvray, D.; Ml, Sigal; Mahé, E.; Resopso, Gem

doi:10.1111/jdv.14021

Cited by 3 publications

(1 citation statement)

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“…Consistent with former findings, 18 our study also reported the inconsistency of PASI and DLQI by revealing a weak correlation between PASI and DLQI (r=0.37, P<0.001). Besides, we found that PASI and DLQI have almost no correlation between values of DLQI >10 from our real-world data (r=0.16, P<0.001), which in accordance with one study reported that patients with DLQI >10 also reported PASI mostly lower than 10.…”

Section: Discussionsupporting

confidence: 92%

Psoriatic Foot Involvement is the Most Significant Contributor to the Inconsistency Between PASI and DLQI: A Retrospective Study from China

Yang¹,

Hu²,

Li³

et al. 2023

CCID

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Background The Psoriasis Area and Severity Index (PASI) and the Dermatology Life Quality Index (DLQI) are important evaluation tools for assessing psoriasis severity and guiding treatment options. However, the scores of PASI and DLQI are often inconsistent. Objective This study aimed to identify the factors affecting the consistency between PASI and DLQI. Methods The retrospective study was based on 4125 patients. We collected the PASI, DLQI, demographic and clinical characteristics data. Results DLQI has a weak correlation with PASI (r=0.37; P <0.001). For the DLQI >10 groups, DLQI has almost no correlation with PASI (r=0.16; P <0.001). There are 43.60% of mild-to-moderate patients (PASI<10) in the DLQI>10 groups. Our adjusted model showed that foot (OR=2.109; 95% CI:1.581–2.815) involvement led to the greatest impairment of QoL except for PASI≥10 (OR=5.547; 95% CI:3.477–8.845). Furthermore, DLQI impairment was associated with female (OR=1.336; 95% CI:1.071–1.667); the age of 20–39 subgroup (OR=1.795; 95% CI:1.100–2.930); psoriatic arthritis (OR=1.718; 95% CI:1.208–2.443); higher income (OR = 1.408; 95% CI: 1.067–1.858); family history of psoriasis (OR=1.460; 95% CI:1.131–1.885). Moreover, the influence of exposed lesions (such as scalp; face; neck; nails; and hands) were positively associated with severely impaired QoL. Conclusion Dermatologists should recognize the underestimated disease burden of psoriasis patients and actively identify and treat mild-to-moderate patients with high burden. In particular, the foot was a significant contributor to the burden.

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Section: Discussionsupporting

confidence: 92%