Characteristics of patients patch tested in the <scp>E</scp>uropean <scp>S</scp>urveillance <scp>S</scp>ystem on <scp>C</scp>ontact <scp>A</scp>llergies (<scp>ESSCA</scp>) network, 2009–2012

Uter, Wolfgang; Gefeller, Olaf; Giménez‐Arnau, Ana; Frosch, Peter J.; Johansen, Jeanne Duus; Schuttelaar, Marie L A; Rustemeyer, Thomas; Filon, Francesca Larese; Dugonik, Aleksandra; Bircher, Andreas J.; Wilkinson, S. M.

doi:10.1111/cod.12409

Cited by 42 publications

(65 citation statements)

References 18 publications

(22 reference statements)

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“…In this analysis, we restricted the set of baseline series allergens to those present in the EBS to increase comparability. Due to the fact that some national groups and departments, respectively, choose to omit certain allergens of the EBS in their baseline series recommendations, the overall yield in these departments will evidently be somewhat lower; further aspects, also including differing selection processes, health systems and methodological issues, have been analysed and discussed in detail in Uter et al . Focussing on the departments specialized in occupational dermatology, a striking variation in the percentage of patients eventually diagnosed with ‘occupational contact dermatitis’ has been noted before by Hegewald et al .…”

Section: Discussionmentioning

confidence: 99%

European Surveillance System on Contact Allergies (ESSCA): results with the European baseline series, 2013/14

Uter

Amario-Hita

Balato

et al. 2017

Acad Dermatol Venereol

114

111

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Section: Discussionmentioning

confidence: 99%

European Surveillance System on Contact Allergies (ESSCA): results with the European baseline series, 2013/14

Uter

Amario-Hita

Balato

et al. 2017

Acad Dermatol Venereol

114

111

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“…Reactions designated as either weak, strong or extreme positive, the symbols being +, ++ and +++, respectively, were classified as allergic, the remainder as non‐allergic. The study period was January 2009 to December 2012, including 12 European countries and, in total, 54 departments (Table ); for further details see Uter, Gefeller and Giménez‐Arnau …”

Section: Methodsmentioning

confidence: 99%

Contact allergy to ingredients of topical medications: results of the European Surveillance System on Contact Allergies (ESSCA), 2009–2012

Uter

Śpiewak

Cooper

et al. 2016

Pharmacoepidemiology and Drug

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Several of the substances warrant routine screening for contact allergy, i.e. patch testing in a baseline series. However, in view of a vast number of other topical agents, additional patch testing with the suspect topical drug preparations (including natural remedies and cosmetics) is warranted. In the event of a positive test to the (pharmaceutical) product, single ingredients should be tested individually to precisely identify the hapten(s). Copyright © 2016 John Wiley & Sons, Ltd.

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“…The prevalences are approximately 8% to 19% in adults and 8% to 10% in children and adolescents in the general population, with a strong predominance in women as compared with men (4‐10 times) and in girls as compared with boys . In dermatitis patients, the prevalence is higher (adults, 12%‐25%; children, 5%‐30%) . Nickel allergy has been less investigated outside of Europe, although persistently high prevalences have been observed in Asia and North America .…”

Section: Epidemiology Of Nickel Allergymentioning

confidence: 99%

Nickel allergy and allergic contact dermatitis: A clinical review of immunology, epidemiology, exposure, and treatment

et al. 2019

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Nickel is the most frequent cause of contact allergy worldwide and has been studied extensively. This clinical review provides an updated overview of the epidemiology, exposure sources, methods for exposure quantification, skin deposition and penetration, immunology, diagnosis, thresholds for sensitization and elicitation, clinical pictures, prevention, and treatment. The implementation of a nickel regulation in Europe led to a decrease in the prevalence of nickel allergy, and changes in the clinical picture and disease severity. Nevertheless, the prevalences of nickel allergy in the European general population are approximately 8% to 19% in adults and 8% to 10% in children and adolescents, with a strong female predominance. Well‐known consumer items such as jewellery and metal in clothing are still the main causes of nickel allergy and dermatitis, although a wide range of items for both private and occupational use may cause dermatitis. Allergic nickel dermatitis may be localized to the nickel exposure site, be more widespread, or present as hand eczema. Today, efficient methods for exposure quantification exist, and new insights regarding associated risk factors and immunological mechanisms underlying the disease have been obtained. Nevertheless, questions remain in relation to the pathogenesis, the persistent high prevalence, and the treatment of severe cases.

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Characteristics of patients patch tested in the European Surveillance System on Contact Allergies (ESSCA) network, 2009–2012

Abstract: Data from one department per country give valuable insights into the spectrum of contact allergy prevalence rates in that country, but are not as representative as national data pooled from several departments.

Cited by 42 publications

References 18 publications

European Surveillance System on Contact Allergies (ESSCA): results with the European baseline series, 2013/14

European Surveillance System on Contact Allergies (ESSCA): results with the European baseline series, 2013/14

Contact allergy to ingredients of topical medications: results of the European Surveillance System on Contact Allergies (ESSCA), 2009–2012

Nickel allergy and allergic contact dermatitis: A clinical review of immunology, epidemiology, exposure, and treatment

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