Scintillations are caused by ionospheric irregularities and can affect the propagation of trans-ionospheric radio signals. One way to understand and predict the impact of such irregularities on Global Navigation Satellite System (GNSS) signals is through the climatological behavior of the ionospheric scintillation indexes during the different phases of a solar cycle. In this work, we investigate the amplitude scintillation index S4 during the full solar cycle 24 at South American (SA) sector, that is featured by the Ionospheric Anomaly (EIA) and by the South Atlantic Magnetic Anomaly (SAMA). We also investigate the daily variation of S4 and two case studies during geomagnetic storms. The results show a significant intensification of amplitude scintillations at northern and southern crest of EIA, especially during the southern hemisphere’s spring/summer seasons, with a higher increase during solar maximum, and after sunset. And particularly at the SAMA region, where the intensity of magnetic field lines is lower, the S4 fluctuations are much higher.