Characteristics of Interactions in the Pectin?Chitosan System

Novel mucoadhesive nasal inserts based on chitosan/hyaluronate polyelectrolyte complexes for peptide and protein delivery

“…Complexes were analysed by FT‐IR spectroscopy to confirm the chitosan/hyaluronic acid interaction. The shift in amine band to 1547 cm − 1 in the spectrum of complexes indicated a change in environment of amine group through its interaction with hyaluronic acid 19,20 . Moreover, an increased intensity of undissociated carboxyl group band (ν C = O at 1716 cm − 1 ) can be observed in the spectrum of chitosan/hyaluronate complex prepared at pH 2.0.…”

Relationship between composition and properties for stable chitosan films containing lipid microdomains

“…The miscibility of materials in polymer blends is dependent on specific interactions between the components such as: the degree of hydrogen bonding, ionic and dipole, p-electron and chargetransfer complexes. From the literature, there is evidence of inter-and intramolecular hydrogen bonding and/or ionic interactions between chitosan and the following homopolymers: silk fibroin, 15 poly(acrylic acid), 16 poly(3-hydroxybutyric acid), 17 poly(ethylene glycol), 18 poly(vinyl pyrrolidone), 19 nylon-4, 20 pectin, 21 poly(caprolactone), 22 poly(vinyl alcohol), 23 and collagen. 24 Chitosan has also been reported to be immiscible with poly(lactic acid), 25 nylon-6, 20 and cellulose.…”

Novel mucoadhesive nasal inserts based on chitosan/hyaluronate polyelectrolyte complexes for peptide and protein delivery

“…The shift in amine band to 1547 cm -1 in the spectrum of complexes indicated a change in environment of amine group through its interaction with hyaluronic acid. [19,20] Moreover, an increased intensity of undissociated carboxyl group band (n C = O at 1716 cm -1 ) can be observed in the spectrum of chitosan/hyaluronate complex prepared at pH 2.0.…”