Characteristics of First Urinary Tract Infection With Fever in Children

Ismaïli, Khalid; Wissing, Karl Martin; Lolin, Ksenija; Le, Phu Quoq; Christophe, Catherine; Lepage, Philippe; Hall, Michelle

doi:10.1097/inf.0b013e318204dcf3

Cited by 51 publications

(53 citation statements)

References 25 publications

(22 reference statements)

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“…We performed 21 MCUG and7 patent (33.3%) has vesicoureteral reflux (VUR) Grade 3 to Grade 5 refluxes, which is in agreement with the findings of previous studies. 20,21 This study shown that it is highly recommended that children with recurrent UTI should undergo RUS and MCUG for early detected of complication and prevention of severe complication like renal scar.…”

Section: Discussionmentioning

confidence: 93%

Clinical Profile and Antibiotics Sensitivity in Childhood Urinary Tract Infection at Dhulikhel Hospital

Singh

Madhup

2015

Kathmandu Univ. Med. J.

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BackgroundUrinary Tract Infection implies presence of actively multiplying organisms in the urinary tract. Although it is infrequently associated with mortality, it is still a significant cause of morbidity. Early diagnosis is critical to preserve renal function of growing kidney. ObjectiveOur purpose was to determine the clinical, microbiologic profile and antibiotic sensitivity of such infections in pediatric Urinary Tract Infection (UTI) patients at Dhulikhel Hospital. MethodsA hospital based prospective descriptive study of 135 children from 2 months to 16 years, with clinical diagnosis of urinary tract infection who visited the pediatric department of Dhulikhel Hospital over the period of 15 months were enrolled in the study. All patients underwent routine urine analysis and culture. Children with recurrent UTI underwent micturating cystourethrogram (MCUG). Children with recurrent UTI of more than two years and with feature of pyelonephritis underwent USG abdomen as well. Complications and response of the treatment was observed in all cases of UTI. All data were entered in Epidata and data analysis was done using spss 16 version. ResultsAmong 135 children, 32.5% were male and 67.4% were female. Fever was the most common presenting symptom in 74.80% of patients followed by dysuria in 54.1%. Among these children 95.6% had significant pyuria and 45% had culture positive infection. Children who showed positive for bacteriuria, Escherichia coli (78.7%) was the most common organism and are more than 80% sensitive to Amikacin, Gentamicin, Ceftriaxone, Ofloxacin, Nalidixic acid, Imipenem and Vancomycin. Co-trimoxazole was the most common drug used for treatment with a mean drug respond time of (mean±S.D) of 2.21±.78 days. 2±±. Children who had recurrent UTI were more prone to develop culture positive UTI (p=0.0001). ConclusionUrinary Tract Infection in female was almost twice more common than in male. Cotrimoxazole was the most common drug used for treatment, sensitivity of this drug was less than 50% for all organisms.

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Section: Discussionmentioning

confidence: 93%

Clinical Profile and Antibiotics Sensitivity in Childhood Urinary Tract Infection at Dhulikhel Hospital

Singh

Madhup

2015

Kathmandu Univ. Med. J.

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“…It is one of the commonest bacterial infection in children especially in those less than 5 years old. As per ISPN guidelines UTI is more common in males during infancy and there is female preponderance thereafter [1][2][3]. Taneja et al in their study of 143 infants with culture positive UTI, found male preponderance, with 116 being males and 27 females [3].…”

Section: Discussionmentioning

confidence: 99%

First Febrile Urinary Tract Infection – Clinico-Biological Correlation with Imaging Studies - A Prospective Study

Vijayakumar¹,

Geminiganesan²,

Priyadarshini³

et al. 2014

J Nephrol Ther

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Febrile urinary tract infection is one of the commonest infections in the childhood. Unrecognized and untreated childhood UTI can lead to scarring of the growing kidneys with subsequent hypertension and renal failure. This study has been done at a tertiary care medical centre to study the clinico -biological and imaging correlation in children with first episode of febrile UTI. Renal function tests, ultrasonogram, DMSA and MCU were done according to ISPN and institutional protocol. Imaging was done on follow up as per need. Majority of the children were found to be in 1 to 5 years age (68%) group and overall there was female preponderance (n=80; 53%). Dysuria was the commonest presentation in febrile UTI and E. coli, the commonest organism isolated. USG was found abnormal in 57.6% of children and DMSA done in acute phase picked up pyelonephritis in 81.5%. MCU revealed VUR in 39% of the study population. The study underlines the importance and efficacy of various investigations apart from the clinical presentation in diagnosing UTI and defining the associated risk factors.

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“…Other less common pathogens found in present study were Staphylococcus species 21(11%) Pseudomonas species 11(6%), and Proteus species 6(3%). Their prevalence is variable in other studies as well (Foxman, 2014;Ismaili et al, 2011).…”

Section: Fig1 Distribution Of Organisms Isolatedmentioning

confidence: 90%

“…Samples were cultured on blood agar and MacConkey agar by using semiquantitative method of culture. Diagnosis of UTI was made by means of positive urine culture (colony count > or = 100000CFU/ml of urine (Ismaili et al, 2011). Organisms were identified by morphology and biochemical reactions.…”

Section: Methodsmentioning

confidence: 99%

Bacteriological Profile of Urinary Tract Infection in Infants

Shah¹,

Wankhede²,

Bhore³

2018

Int.J.Curr.Microbiol.App.Sci

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Characteristics of First Urinary Tract Infection With Fever in Children

Abstract: Girls represent 63% of cases with first UTI. For 91% of UTIs, Escherichia coli is held responsible with a high rate of resistance to ampicillin and trimethoprim/sulfamethoxazole. US is an excellent screening tool that allows avoidance of unjustified voiding cystourethrography studies.

Cited by 51 publications

References 25 publications

Clinical Profile and Antibiotics Sensitivity in Childhood Urinary Tract Infection at Dhulikhel Hospital

Clinical Profile and Antibiotics Sensitivity in Childhood Urinary Tract Infection at Dhulikhel Hospital

First Febrile Urinary Tract Infection – Clinico-Biological Correlation with Imaging Studies - A Prospective Study

Bacteriological Profile of Urinary Tract Infection in Infants

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