“…Evidence already reveals that there are a number of challenges to be aware of when digital technologies are used by older adults including physical issues such as decline in manual dexterity and eyesight and decreasing cognitive capabilities, frustration, the need for specific training, age, gender, dry finger skin, and age-related cognitive motor skills [2,[18][19][20][21][22], all factors likely to affect the performance of RT and IIV RT tests using a touch screen platform and thus their clinical validity, usefulness, and robustness. Furthermore, RT research has revealed many participant and methodology-related factors capable of significantly affecting RT study outcome including: the test item, the environment, response requirements, participant and tester, feedback, concurrent disease, medication, abnormal visual and attention-related processes, caffeine, depression, personality, and gender [11][12][13][23][24][25][26][27].…”