Characteristics of chitosan fiber and their effects towards improvement of antibacterial activity

Li, Jianhui; Fu, Jimin; Tian, Xiao; Hua, Tao; Poon, Tszyin; Koo, Mingkin; Chan, Wai Lun

doi:10.1016/j.carbpol.2021.119031

Cited by 53 publications

(27 citation statements)

References 42 publications

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“…It has been found that bacterial cells growing within biofilms secrete different surface molecules and virulence factors and exhibit low growth rates, which enhance their pathogenicity by several folds [ 23 ]. Chitosan is a linear polysaccharide that is obtained from the deacetylation of chitin, a naturally occurring polymer present in the shells of prawns and other crustaceans [ 24 ]. It is one of the most commonly used biopolymers in a wide range of applications, including fabrics, cosmetics, water treatment, and food processing [ 25 , 26 , 27 ].…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Silver Nanoparticles Based on Chitosan: Antibacterial, Antibiofilm, Antifungal, Antioxidant, and Wound-Healing Activities

Shehabeldine

Salem

Ali

et al. 2022

JoF

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The purpose of this study is to create chitosan-stabilized silver nanoparticles (Chi/Ag-NPs) and determine whether they were cytotoxic and also to determine their characteristic antibacterial, antibiofilm, and wound healing activities. Recently, the development of an efficient and environmentally friendly method for synthesizing metal nanoparticles based on polysaccharides has attracted a lot of interest in the field of nanotechnology. Colloidal Chi/Ag-NPs are prepared by chemical reduction of silver ions in the presence of Chi, giving Chi/Ag-NPs. Physiochemical properties are determined by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), dynamic light scattering (DLS), and scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX) analyses. TEM pictures indicate that the generated Chi/Ag-NPs are nearly spherical in shape with a thin chitosan covering around the Ag core and had sizes in the range of 9–65 nm. In vitro antibacterial activity was evaluated against Staphylococcus aureus and Pseudomonas aeruginosa by a resazurin-mediated microtiter plate assay. The highest activity was observed with the lowest concentration of Chi/Ag-NPs, which was 12.5 µg/mL for both bacterial strains. Additionally, Chi/Ag-NPs showed promising antifungal features against Candida albicans, Aspergillus fumigatus, Aspergillus terreus, and Aspergillus niger, where inhibition zones were 22, 29, 20, and 17 mm, respectively. Likewise, Chi/Ag-NPs revealed potential antioxidant activity is 92, 90, and 75% at concentrations of 4000, 2000, and 1000 µg/mL, where the IC50 of Chi/Ag-NPs was 261 µg/mL. Wound healing results illustrated that fibroblasts advanced toward the opening to close the scratch wound by roughly 50.5% after a 24-h exposure to Chi/Ag-NPs, greatly accelerating the wound healing process. In conclusion, a nanocomposite based on AgNPs and chitosan was successfully prepared and exhibited antibacterial, antibiofilm, antifungal, antioxidant, and wound healing activities that can be used in the medical field.

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Section: Introductionmentioning

confidence: 99%

Multifunctional Silver Nanoparticles Based on Chitosan: Antibacterial, Antibiofilm, Antifungal, Antioxidant, and Wound-Healing Activities

Shehabeldine

Salem

Ali

et al. 2022

JoF

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“…The CS (1%) solution showed a bacterial inhibition zone diameter larger than FA on both E. coli and B. cereus ( Figure 6 B). The CS inhibition zones on E. coli and B. cereus were 18.51 mm and 14.81 mm, respectively, while in FA the inhibition zones were 10.16 mm, and 13.57 mm, respectively [ 64 ].…”

Section: Resultsmentioning

confidence: 99%

New Isolated Shrimp (Litopenaeus setiferus) Chitosan-Based Films Loaded with Fly Ash for Antibacterial Evaluation

Alterary

Marei

2022

Polymers

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New three fabricated chitosan (CS) loaded with fly ash (FA) films were developed in this study. The shell waste of white shrimp was used as a precursor for the isolation of chitin and converted into chitosan by carrying out a deacetylation process. The formation of chitosan was conducted by various preparation steps deproteinization, demineralization, and deacetylation. The degree of deacetylation was found to be 95.2%. The obtained chitosan was used to prepare three different chitosan loaded-fly ash films. The prepared films contained various fly ash: chitosan ratios (2:1, FA-CSF1), (1:1, FA-CSF2), and (1:2, FA-CSF3). The obtained films were characterized using FTIR, XRD, and SEM. The micrograph images of the formed films showed spherical particles with an average size of 10 µm. The surface area, adsorption-desorption properties, thermal stability, and water/fat binding features of the fabricated chitosan films were studied. The results revealed that the prepared films displayed typical BET graphs with surface areas ranging from 2.436 m2 g−1 to 8.490 m2 g−1. The fabricated FA-CSF films also showed high thermal stability at temperatures up to 284.9 °C and excellent water/fat binding capacities. The antibacterial potential of the designed films was screened against E. coli (Gram-negative) and B. cereus (Gram-positive) bacterial strains. The tested solution of CS (1%) exhibited inhibition zones for E. coli and B. cereus as 18.51 mm and 14.81 mm, respectively, while in FA solution (1%), the inhibition zones were found to be 10.16 mm, and 13.57 mm, respectively. The results encourage and open up the new and promising areas of research for applying chitosan extracted from waste materials in biological applications.

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“…De acordo com Li et al, (2022), investigou suas composições e suas características mecânicas, confirmando seu efeito bacteriostática no S. aureus e bactericida na E. coli correlacionando com sua fibra, MW e DD, contribuindo para averiguar a eficiência em razão da sua estrutura, incentivando a empregabilidade e aperfeiçoamento da mesma. A ação bactericida contra S. aureus desestabiliza suas estruturas intracelulares e parede celular, infere-se que essa representa um potencial biopolímero como agente antibacteriano a fim de combater e auxiliar no controle da resistência ao ambiente hospitalar (Oliveira et al,2019).…”

Section: Atividade Antimicrobiana Da Quitosanaunclassified

Pneumonia Associada à Ventilação Mecânica (PAVM) assistida pela quitosana

Mendes¹,

Sousa²,

Rodrigues³

et al. 2022

RSD

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Introdução: A pneumonia associada à ventilação mecânica (PAVM) é uma das preponderantes causas das infecções nosocomiais em UTIs que ocasionando elevação do tempo de internação, despesas médicas, crescimentos nos índices de morbilidade e mortalidade, com o aumento de bactérias resistentes aos antibióticos, corrobora na aplicação de novos biomateriais, com isso, a quitosana é estudada por constituir por diversas propriedades funcionais, como antimicrobiana. Metodologia: A pesquisa realizada é uma revisão sistemática através da consulta em bancos de dados online para o levantamento das informações. As principais bases de dados de periódicos utilizados para as buscas ativas dos artigos foram: ANVISA, OMS, PUBMED, Science Direct, SCIELO. Resultados e discussões: A interação microbiana dentro do biofilme colabora para a PAVM, nesse sentido ocorre uma implicação na terapia antimicrobiana, entretanto a resistência aos fármacos utilizados revalida a necessidade de se encontrar novos agentes antimicrobianos, a quitosana e os seus derivados possuem versatilidade, baixo custo e vasto espectro de atividade antimicrobiana contra bactérias gram-positivas, gram-negativas, fungos filamentosos e leveduras. Conclusão: verifica-se que uma forma provável de combater as infecções bacterianas relacionadas a ventilação mecânica é a quitosana e seus derivados, que possuem atividades antimicrobianas relevantes e grande potencial para utilização dos mesmos no combate a tenacidade de microorganismos.

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Characteristics of chitosan fiber and their effects towards improvement of antibacterial activity

Cited by 53 publications

References 42 publications

Multifunctional Silver Nanoparticles Based on Chitosan: Antibacterial, Antibiofilm, Antifungal, Antioxidant, and Wound-Healing Activities

Multifunctional Silver Nanoparticles Based on Chitosan: Antibacterial, Antibiofilm, Antifungal, Antioxidant, and Wound-Healing Activities

New Isolated Shrimp (Litopenaeus setiferus) Chitosan-Based Films Loaded with Fly Ash for Antibacterial Evaluation

Pneumonia Associada à Ventilação Mecânica (PAVM) assistida pela quitosana

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