Characteristics of children hospitalized with dengue fever in an outbreak in Rio de Janeiro, Brazil

Abstract

During a dengue epidemic in Rio de Janeiro in 2007-2008 the Instituto de Puericultura e Pediatria Martagão Gesteira Hospital was a reference for admitted children. The World Health Organization (WHO) considered several manifestations as warning signs of severe dengue This is a retrospective cohort study of all children admitted with dengue fever. Clinical variables considered warning signs by WHO were evaluated in the multivariate analysis, to investigate if they were independently associated with severe dengue. One hundred and eighty one children were admitted, aged from 4 months to 15 years; 30 were classified as severe dengue. Abdominal pain (OR=2.63, 95% CI 1.06-6.53) and lethargy (OR=3.40, 95% CI 1.45-7.99) were independently associated with severe dengue.

Predictive Symptoms and Signs of Severe Dengue Disease for Patients with Dengue Fever: A Meta-Analysis

“…Sixteen articles published between 2000 and 2012 were ultimately included in this meta-analysis based on the inclusion and exclusion criteria (Figure 1). The final collection consists of 10 prospective [9–11, 17–23], four retrospective [7, 8, 24, 25], and two cross-sectional studies [26, 27]. As listed in Table 1, eight of the 16 studies reported on a population study of children, two on adults and six on both.…”

“…For instance, Khan et al found that male DF patients were more likely to progress into DHF (OR: 2.3, 95% CI: 1.1–4.5, P value 0.021) [6], while there was no association with SDD [7, 8]. The frequencies of symptoms/signs of vomiting/nausea, abdominal pain, skin rashes, and bleeding were also found to be correlated with SDD [6–11].…”

Diagnosis of dengue: an update

“…They estimated that 43.9% of the mild dengue cases could have been prevented from hospitalization in 2004. The authors followed up this study with a [150,152] 78.0|22.0% †…”

Re : Dengue Haemorrhagic Fever presenting as Acute Abdomen = رد على : البطن الحادة كعرض لحمى الدنك النزفية

“…8,9 The severity of dengue is strongly relating to the presence of abdominal pain. 10 In a recent article from India, it was reported as being seen in up to 70% of the paediatric cases. 8 Conclusively, acute abdomen can be a first presentation of dengue and conservative management can be used similar to general dengue cases.…”