Characteristics of cervical intervertebral disc signal intensity: an analysis of T2-weighted magnetic resonance imaging in 5843 asymptomatic Chinese subjects

Investigating the characteristics of mild intervertebral disc degeneration at various age stages using single-cell genomics

“…Intervertebral disc degeneration is often thought to occur mainly in the elderly population. However, there is a gradual increase in the proportion of young patients ( Liu et al, 2023 ). In recent years, single-cell sequencing has been increasingly used in the field of intervertebral disc degeneration ( Wang et al, 2023 ; Jiang et al, 2022 ; Guo et al, 2023b ; Gao et al, 2022 ; Gan et al, 2021 ).…”

Quantitative Assessment of Intervertebral Disc Degeneration Using the Disc Signal Intensity Index in Patients With Spine-Related Pain

“…In previous studies, the ROIs for disc signal intensity measurements were defined as the whole or central part of the nucleus pulposus and did not include the annulus fibrosus [ 13 , 15 , 16 ]. However, the signal intensity is not constant, even in the nucleus.…”

Atlantoaxial Joint Arthropathy With Cervicogenic Headache

“…The MRI (Figure 2) revealed mild multilevel degenerative disc disease and associated bulging without significant stenosis or other associated acute findings to explain her ongoing symptoms (Bogduk, 2014;Garrick et al, 2012;Hermenau & Grauer, 2012;Knackstedt et al, 2012;Liu et al, 2023;Mesregah et al, 2022;Verma et al, 2021) Given the significance of presenting symptoms, with reproducible focal left sided pain further exacerbated with clinical testing, a single open mouth (odontoid) view was obtained with pertinent findings of severe left C1-2 arthropathy (Figure 3). With this, the utility of image guided corticosteroid injection, in combination with focused physical therapy program, was discussed with the patient who was amenable to the outlined course of interventions and treatment.…”