Characteristics of breath sound in infants with risk factors for asthma development

Shioya, Hiromi; Tadaki, Hiromi; Yamazaki, Fusae; Miyamoto, Manabu; Yoshihara, Shigemi; Enseki, Mayumi; Tabata, Hideyuki; Hirai, Kota; Furuya, Hiroyuki; Katô, Masahiko; Ito, Sachiko; Mochizuki, Hiroyuki

doi:10.1016/j.alit.2018.07.011

Cited by 15 publications

(28 citation statements)

References 24 publications

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“…We ultimately analyzed 398 infants, consisting of 283 who had no history of recent ARI and 115 who had a history of ARI (Table ). A total of 116 subjects had a wheezing history, consisting of 68 without ARI and 48 with ARI on the day of the examination.…”

Section: Resultsmentioning

confidence: 99%

“…A total of 443 infants (mean age, 9.9 months; range, 3–24 months, male : female, 232:211) who attended an infant health checkup at Isehara Municipal Clinic, Uchida Iin Y Child Clinic, National Hospital Organization Yokohama Medical Center, Yamato Municipal Hospital and Dokkyo Medical University between 1 January 2012 and 31 March 2016, and who agreed to participate were included in this study . The parents understood the purpose of the study and participated in the study.…”

Section: Methodsmentioning

confidence: 99%

“…The exclusion criteria were as follows: infants with severe diseases of lung, heart and other organs and with a fever and/or respiratory symptoms. The results of a breath sound spectrum analysis at the first visit of these 443 infants have been reported …”

Section: Methodsmentioning

confidence: 99%

“…). The presence of ARI was judged by the parents based on the existence of upper and lower airway symptoms, such as nasal discharge, nasal congestion, moist cough, shortness of breath and wheezing with or without a fever …”

Section: Methodsmentioning

confidence: 99%

“…An original Japanese questionnaire based on the American Thoracic Society‐for the Division of Lung Diseases (ATS‐DLD) was used (Table ). Question 1 asked about the history of ARI at the time of the visit.…”

Section: Methodsmentioning

confidence: 99%

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Objective evaluation of wheezing in normal infants

Murayama¹,

Shioya

Tadaki

et al. 2019

Pediatrics International

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Background: To evaluate the frequency of wheezing in infants, the presence of wheezing was examined in normal infants using a breath sound analyzer, Methods: A total of 443 infants (age range, 3-24 months) were included in the present study. The existence of audible wheezing and faint wheezing/inaudible wheezing-like noises (FW) was confirmed on chest auscultation and a sound spectrogram. The breath sound parameters of the sound spectrum, frequency limiting 99% of power spectrum (F 99 ), roll-off from 600 to 1,200 Hz (slope) and spectrum curve indices, total area under the curve of dB data (A 3 /A T and B 4 /A T ), and ratio of power and frequency at 50% and 75% of the highest frequency of the power spectrum (RPF 50 and RPF 75 ) were calculated. Using an original Japanese questionnaire, we examined the characteristics of the airway condition of all infants. Results: Finally, a total of 398 infants were analyzed in the present study, and 283 were in good health while 115 had acute respiratory infection (ARI) in the last 7 days. No infants had audible wheezing on auscultation. Three infants without ARI (1.1%) and 10 infants with ARI (8.7%) had FW. In the evaluation of breath sound parameters, there were no marked differences between the infants with and without FW. Conclusions: Using a breath sound analyzer, wheezing and FW were recognized in only a few infants in good health. Infants recognized to have audible wheezing in daily practice may be at risk of developing recurrent wheezing/asthma. A total of 443 infants (mean age, 9.9 months; range, 3-24 months, male : female, 232:211) who attended an infant

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 3 more Smart Citations

Objective evaluation of wheezing in normal infants

Murayama¹,

Shioya

Tadaki

et al. 2019

Pediatrics International

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View full text Add to dashboard Cite

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Lung sound analysis in infants with risk factors for asthma development

Miyamoto

Yoshihara

Shioya

et al. 2021

Health Science Reports

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Background and objectives Using a lung sound analysis, the prognosis of asthma was investigated in infants with risk factors for asthma development by a long‐term observation. Methods A total of 268 infants were included (median age: 8 months old). The lung sound parameters (the ratio of the third and fourth area to the total area under the curve [A 3 /A T and B 4 /A T ], and the ratio of power and frequency at 50% and 75% of the highest frequency [RPF 50 and RPF 75 ]) were evaluated at the first visit. At 3 years old, using a questionnaire, we examined the relationship between the lung sound parameters and risk factors of asthma development. Results Among the 268 infants, 175 infants were in good health and 93 had a history of acute respiratory infection (ARI) within 7 days at the first visit. Among the 3‐ to 12‐month‐old infants with an ARI, the A 3 /A T , B 4 /A T values in those with a history of asthma/asthmatic bronchitis, atopic dermatitis, and atopy were smaller than in the infants without such histories. Among the 13‐ to 24‐month‐old infants with an ARI, the A 3 /A T and B 4 /A T values in those with a wheezing history were larger than in the infants without such a history. Conclusions The characteristics of the lung sounds in infants with risk factors for asthma development were demonstrated over long‐term follow‐up. Lung sound analyses may be useful for assessing the airway condition of infants.

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Breath sound analyses of infants with respiratory syncytial virus acute bronchiolitis

Kuruma

Otomo²,

Sakama³

et al. 2022

Pediatric Pulmonology

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Introduction:The reliability of a breath sound analysis using an objective method in infants has been reported.Objective: Breath sounds of infants with respiratory syncytial virus (RSV) acute bronchiolitis were analyzed via a breath sound spectrogram to evaluate their characteristics and examine their relationship with the severity. Subjects and Methods:We evaluated the inspiratory and expiratory breath sound parameters of 33 infants diagnosed with RSV acute bronchiolitis. The sound powers of inspiration and expiration were evaluated at the acute phase and recovery phase of infection. Furthermore, the relationship between the breath sound parameters and the clinical severity of acute bronchiolitis was examined.Results: Analyses of the breath sound spectrogram showed that the power of expiration as well as the expiration-to-inspiration sound ratio in the mid-frequency (E/I MF) was increased in the acute phase and decreased during the recovery phase.The E/I MF was inversely correlated with the SpO 2 and positively correlated with the severity score. Conclusion:In infants with RSV acute bronchiolitis, the sound power of respiration was large at the acute phase, significantly decreasing in the recovery phase. In 61% of participants, nonuniform, granular bands were shown in the low-pitched region of the expiratory spectrogram.

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Characteristics of breath sound in infants with risk factors for asthma development

Abstract: Our data highlight the characteristics of breath sounds in infants with risk factors for asthma. The breath sound analysis may be useful for assessing the airways of infants for asthma development.

Cited by 15 publications

References 24 publications

Objective evaluation of wheezing in normal infants

Objective evaluation of wheezing in normal infants

Lung sound analysis in infants with risk factors for asthma development

Breath sound analyses of infants with respiratory syncytial virus acute bronchiolitis

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