Characteristics of bacterial colonization after indwelling double-J ureteral stents for different time duration

Shabeena, K S; Bhargava, Rahul; Manzoor, Muhammed A.P.; Mujeeburahiman, M

doi:10.4103/ua.ua_158_17

Cited by 30 publications

(16 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Double-J stents in kidney transplant recipients significantly reduce urologic complications of transplant surgery such as urine leaks and ureteric stenosis. [10,11] However, it may be associated with a few complications such as suprapubic pain, vesicoureteric reflux, stent migration, encrustation, stent fracture, and urinary infections hence the rationale for using the procedure in selected patients. [10,11] Table II: Pattern of sensitivity of the bacterial isolates This study showed a high prevalence of urine colonisation in post-kidney transplant patients with double-J stents in our practice.…”

Section: Discussionmentioning

confidence: 99%

Urine Bacteriology in Post-Kidney Transplant Patients with Double-J Stents

Abu¹,

Igbokwe²,

Olatise³

et al. 2021

Ann Health Res

View full text Add to dashboard Cite

Background: Kidney transplantation is the gold standard treatment modality for patients with end-stage renal disease. Ureteric stenting is commonly used during kidney transplantation to reduce the incidence of ureteric complications post-transplantation. The presence of ureteric stents could be complicated by bacterial colonisation and urinary tract infections. Objective: To identify the urinary flora in patients with double-J stents following kidney transplantation and establish bacteria colonisation and their antimicrobial susceptibility. Methods: Over one-year, single urine samples of consecutive 100 post-renal transplant patients were subjected to bacteriologic analysis. Early morning midstream urine was obtained into a sterile bottle from all the participants for laboratory analysis. Results: The mean age of post kidney transplantation patients was 47.6 ±12.3 years. Hypertension and diabetes were the commonest co-morbidities associated with End-Stage-Renal-Disease (ESRD), accounting for 61% and 28%, respectively. E. coli was the commonest isolate (70.4%). Microbiological evidence of Urinary Tract Infection (UTI) revealed by pyuria (pus cells >4/HPF) was found in 40.9%. Tigecycline, nitrofurantoin and tetracycline showed the highest sensitivity pattern in 9%, 8% and 8%, respectively, with significant resistance against cephalosporins and fluoroquinolones. Conclusion: The fourth week of double-J ureteric stent insertion in kidney transplant recipients showed a high incidence of urinary bacterial colonisation.

show abstract

Section: Discussionmentioning

confidence: 99%

Urine Bacteriology in Post-Kidney Transplant Patients with Double-J Stents

Abu¹,

Igbokwe²,

Olatise³

et al. 2021

Ann Health Res

View full text Add to dashboard Cite

show abstract

“…Shabeena et al . had shown that leaving indwelling ureteral stents longer increases the risk for bacterial colonization [ 20 ]. Varying length of stent placement within our study population may have been a confounding factor in our results.…”

Section: Resultsmentioning

confidence: 99%

Antibiotic prophylaxis is not associated with reduced urinary tract infection-related complications after cystectomy and ileal conduit

Kirkpatrick

Haynes

2018

Bladder

View full text Add to dashboard Cite

OBJECTIVES: Majority of complications after ileal conduit urinary diversion with cystectomy are related to urinary tract infections (UTIs). Controversy exists regarding use of prophylactic antibiotics after surgery. We determined if prophylactic antibiotic use during ureteral stent placement after ileal conduit urinary diversion decreased incidence of UTI-related complications. METHODS: We retrospectively identified 75 consecutive patients who underwent ileal conduit urinary diversion with cystectomy at our institution from 2010 to 2016. Patients were stratified based on presence or absence of a UTI-related complication in the 90-day postoperative period. Means were compared with independent t-test and proportions with chi-square analysis. Multivariate logistic regression was performed to determine independent predictors of UTI-related complications. RESULTS: Forty-five patients (60%) were prescribed prophylactic antibiotics after surgery. Mean duration of antibiotic use was 15 d, and mean duration of ureteral stenting was 25 d. Most common antibiotics used included fluoroquinolones (n = 23, 30.7%) followed by sulfamethoxazole-trimethoprim (n = 14, 18.7%). Rate of 90-day UTI-related complications was 36% (n = 27), and 90-day UTI-related readmission rate was 14.7% (n = 11). On bivariate and multivariate analysis, prophylactic antibiotic use was not associated with reduced 90-day UTI-related complications (P > 0.05). Patients prescribed prophylactic antibiotics had increased incidence of Clostridium difficile infections in the 90-day postoperative period compared to controls (20% vs. 3.3%; P = 0.038). CONCLUSIONS: Prophylactic antibiotic use after ileal conduit urinary diversion with cystectomy was not associated with reduced UTI-related complications, and rate of Clostridium difficile infections was higher in this patient cohort. The effect of early removal of ureteral stents on UTI risk still has to be elucidated.

show abstract

“…When assessing a BUS, stent fragments carry the biofilm which covers all ureteral stents and causes the bacteria embedded in the biofilm to become free or results in planktonic bacteria in the urine by breaking the integrity of the biofilm. Consequently, if our results are compared with scientific literature on the bacterial colonisation of ureteral stents with a similar stenting time (29.4% [ 22 ], 42% [ 20 ], 46.2% [ 21 ], 58.6% [ 23 ], 82.9% [ 10 ], 98.5% [ 20 ], 100% [ 24 ]), experimental values are not as high as they initially seemed to be, since they take into account the continuous fragmentation of the biofilm layer. One final factor could explain these disappointing, asymptomatic bacteriuria results: all study animals were females.…”

Section: Discussionmentioning

confidence: 97%

“…Firstly, it is necessary to compare them with other results described in clinical trials evaluating 30–60 days of standard ureteral stenting: 21.9% [ 18 ], 24.3% [ 10 ], 23.6% [ 19 ], 28% [ 20 ], 45.8% [ 21 ]. In this regard, our positive asymptomatic bacteriuria rate was within an elevated range: BraidStent®-H values were 1.5–2 times higher than the bacteriuria rate, except for in the study by Shabeena (45.8%) [ 21 ]. Nevertheless, a second, very important factor must be considered in order to critically assess these unsatisfactory results.…”

Section: Discussionmentioning

confidence: 99%

Comparative assessment of biodegradable-antireflux heparine coated ureteral stent: animal model study

Soria

Cruz

Romeu³

et al. 2021

BMC Urol

View full text Add to dashboard Cite

Background Double J ureteral stents are widely used on urological patients to provide drainage of the upper urinary tract. Unfourtunately, ureteral stents are not free from complications, as bacterial colonization and require a second procedure for removal. The purpose of the current comparative experimental study is to evaluate a new heparin-coated biodegradable antireflux ureteral stent (BraidStent®-H) to prevent urinary bacterial colonization. Methods A total of 24 female pigs were underwent determination of bacteriuria and nephrosonographic, endoscopic and contrast fluoroscopy assessment of the urinary tract. Afterward, were randomly assigned animals to Group-I, in which a 5Fr double-pigtail ureteral stent was placed for 6 weeks, or Group-II, in which a BraidStent®-H was placed. Follow-up assessments were performed at 1, 3, 6, 8, 12 weeks. The final follow-up includes the above methods and an exhaustive pathological study of the urinary tract was accomplished after 20 weeks. Results Bacteriuria findings in the first 48 h were significant between groups at 6 h and 12 h. Asymptomatic bacteriuria does not reach 100% of the animals in Group-II until 48 h versus Group-I where it appears at 6 h. The weekly bacteriuria mean rate was 27.7% and 44.4% in Group I and II respectively, without statistical significance. In Group II there were no animals with vesicoureteral reflux, with statistical significance at 3 and 6 weeks with Group-I. The 91.2% of stents in Group-II were degraded between 3 and 6 weeks, without obstructive fragments. Distal ureteral peristalsis was maintained in 66.6–75% in Group-II at 1–6 weeks. Conclusions The heparin coating of BraidStent® allows an early decrease of bacterial colonization, but its effectiveness is low at the long term. Heparin coating did not affect scheduled degradation rate or size of stents fragments. BraidStent®-H avoids the side effects associated with current ureteral stents, thus should cause less discomfort to patients.

show abstract

Characteristics of bacterial colonization after indwelling double-J ureteral stents for different time duration

Cited by 30 publications

References 8 publications

Urine Bacteriology in Post-Kidney Transplant Patients with Double-J Stents

Urine Bacteriology in Post-Kidney Transplant Patients with Double-J Stents

Antibiotic prophylaxis is not associated with reduced urinary tract infection-related complications after cystectomy and ileal conduit

Comparative assessment of biodegradable-antireflux heparine coated ureteral stent: animal model study

Contact Info

Product

Resources

About