Characteristics of acute congestive heart failure with normal ejection fraction and less elevated B-type natriuretic peptide

Shimamoto, Ken; Koike, Natsuha; Mizuochi, K.; Honma, Miho; Kasai, Yufuko; Sakai, Akiko; Fujita, Etsuko; Kawana, Masatoshi

doi:10.1186/1471-2261-9-2

Cited by 4 publications

(4 citation statements)

References 35 publications

(33 reference statements)

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“…We believe this was because the high SpVi group had more men, higher body mass index and prevalence of a history of open-heart surgery. It is well known that being male, 23) obesity, 24,25) and a prior history of open-heart surgery 26) are associated with low BNP. We speculate that increased splenic volume reflects venous congestion due to right heart failure, which might result in readmission for heart failure.…”

Section: Discussionmentioning

confidence: 99%

Splenic Volume Index Determined Using Computed Tomography upon Admission Is Associated with Readmission for Heart Failure Among Patients with Acute Decompensated Heart Failure

et al. 2021

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The spleen is associated with inflammation, and the size of the spleen is affected by hemodynamic congestion and sympathetic stimulation. However, the association between splenic size and prognosis in patients with heart failure remains unknown. Between January 2015 and March 2017, we analyzed 125 patients with acute decompensated heart failure who were assessed by computed tomography (CT) on the day of admission. The spleen was measured by 3-dimensional CT and then the patients were assigned to groups according to their median splenic volume indexes (SpVi; splenic volume/body surface area). We then compared their baseline characteristics and rates of readmission for heart failure after one year. The median SpVi was 63.7 (interquartile range: 44.7-95.3) cm 3 /m 2 . Age did not significantly differ between the groups. Patients with a high SpVi had more significantly enlarged left atria and left ventricles. Multiple regression analysis identified significant positive correlations between SpVi and posterior wall thickness as well as left ventricular mass index. Kaplan-Meier analysis revealed lower event-free rates in the patients with a high, than a low SpVi (P = 0.041, log-rank test). After adjustment for potential cofounding factors, SpVi was independently associated with readmission for heart failure (Hazard ratio, 2.25; 95% confidence interval, 1.01-5.02; P = 0.047). In conclusion, increased splenic volume is independently associated with readmission for heart failure among patients with acute decompensated heart failure.

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Section: Discussionmentioning

confidence: 99%

Splenic Volume Index Determined Using Computed Tomography upon Admission Is Associated with Readmission for Heart Failure Among Patients with Acute Decompensated Heart Failure

et al. 2021

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“…28 CHF is represented as a reduction in the contractility of left ventricle below the nominal value. 3 Therefore, CHF provides a significant drop in CO to 1.5 L min -1 and MAP reduced to 99.0 mmHg as well. The target sites of SNP effect are the unstressed blood volume of large veins, the arterioles resistance, and the pulmonary capillaries resistance which affects the arterial blood pressure.…”

Section: Patient's Modelmentioning

confidence: 96%

Section: Automated Drug Infusion Systemmentioning

confidence: 96%

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Automated Cardiac Drug Infusion System Using Adaptive Fuzzy Neural Networks Controller

Karar

El-Brawany

2011

Biomed Eng Comput Biol

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This paper presents a fuzzy neural network (FNN) control system to automatically manage the hemodynamic variables of patients with hypertension and congestive heart failure (CHF) via simultaneous infusion of cardiac drugs such as vasodilators and inotropic agents. The developed system includes two FNN sub-controllers for regulating cardiac output (CO) and mean arterial pressure (MAP) by cardiac drugs, considering interactive pharmacological effects. The adaptive FNN controller was tested and evaluated on a cardiovascular model. Six short-term therapy conditions of hypertension and CHF are presented under different sensitivities of a vasodilator drug. The results of the automated system showed that root mean square errors were ≤ 5.56 mmHg and ≤ 0.22 L min-1 for regulating MAP and CO, respectively, providing short settling time responses of MAP (≤ 10.9 min) and CO (≤ 8.22 min) in all therapy conditions. The proposed FNN control scheme can significantly improve the performance of cardiac drug infusion system.

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Low NT-proBNP levels: An early sign for the diagnosis of ischemic heart failure

Zheng

Cen

et al. 2017

International Journal of Cardiology

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Characteristics of acute congestive heart failure with normal ejection fraction and less elevated B-type natriuretic peptide

Cited by 4 publications

References 35 publications

Splenic Volume Index Determined Using Computed Tomography upon Admission Is Associated with Readmission for Heart Failure Among Patients with Acute Decompensated Heart Failure

Splenic Volume Index Determined Using Computed Tomography upon Admission Is Associated with Readmission for Heart Failure Among Patients with Acute Decompensated Heart Failure

Automated Cardiac Drug Infusion System Using Adaptive Fuzzy Neural Networks Controller

Low NT-proBNP levels: An early sign for the diagnosis of ischemic heart failure

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