Characteristics of abnormal post‐stent optical coherence tomography findings in hemodialysis patients

Matsuhiro, Yutaka; Matsunaga‐Lee, Yasuharu; Nakamura, Daisuke; Yano, Masamichi; Yamato, Masaki; Egami, Yasuyuki; Shutta, Ryu; Sakata, Yasushi; Nishino, Masami; Tanouchi, Jun

doi:10.1002/ccd.28188

Cited by 4 publications

(3 citation statements)

References 17 publications

(33 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…During imaging acquisition, blood was displaced by an injection of contrast media. In general, in patients presenting with Thrombolysis In Myocardial Infarction (TIMI) flow of grades 2 and 3, OCT was performed before any intervention, whereas for cases with a TIMI flow of grades 0 or 1, OCT was performed after pre-dilatation using only small balloons (≤ 2.0 mm) 8,9) . The images were calibrated by an automated adjustment of the Z-offset, and the automated pullback was set at 20 mm/s.…”

Section: Oct Image Acquisitionmentioning

confidence: 99%

Predictors for the Early Development of Neoatherosclerosis After Newer-generation Drug-eluting Stent Implantation

Yanagawa

Nakamura

Egami

et al. 2022

Journal of Coronary Artery Disease

Self Cite

View full text Add to dashboard Cite

Several clinical trials have found that percutaneous coronary intervention (PCI) using drug-eluting stents (DESs) drastically improve the clinical outcome 1,2) . However, the development of neoatherosclerosis (NA) after DES implantation has been a recent clinical problem in PCI, even when using second-or third-generation DESs [3][4][5] . Several clinical trials have reported predictors for the late development of NA after stent implantation 6) . However, predictors for the early development of NA with second-and third-generation DESs remain unclear.Optical coherence tomography (OCT) has a 10-fold higher resolution than intravascular ultrasound (IVUS) and can allow the detailed assessment of the characteristics of lesion plaques or in-stent tissue protrusions. Furthermore, irregular in-stent protrusion (IP) after stent implantation has been reported to be associated with adverse cardiac events 7) .In the present study, we explored the predictive fi ndings for the early development of NA after newer-generation DES implantation by comparing serial OCT fi ndings. II. Methods 1. Patient population From among 1,296 consecutive patients who underwent PCI in our institution from December 2015 and August 2018, we enrolled 123 consecutive patients (140 lesions) with second-and third-generation DESs with available fi ndings for both pre-and post-stenting OCT and who had undergone eight-month follow-up OCT. OCT-guided PCI was indicated if approved by both

show abstract

Section: Oct Image Acquisitionmentioning

confidence: 99%

Predictors for the Early Development of Neoatherosclerosis After Newer-generation Drug-eluting Stent Implantation

Yanagawa

Nakamura

Egami

et al. 2022

Journal of Coronary Artery Disease

Self Cite

View full text Add to dashboard Cite

show abstract

“…We previously published the details of the OCT analysis. [7,8] All variables were analyzed at lesion level. In brief, the cross-sectional OCT images were analyzed at 1-mm intervals within the entire target segment of the pre-procedural, post-procedural, and 3-month follow-up OCT data.…”

Section: Oct Image Analysismentioning

confidence: 99%

Early vascular healing of ultra-thin strut polymer-free sirolimus-eluting stents in acute coronary syndrome: USUI-ACS study

Matsuhiro

Egami

Okamoto

et al. 2021

Preprint

Self Cite

View full text Add to dashboard Cite

Purpose:Ultra-thin strut polymer-free sirolimus eluting stent (UPF-SES) have two novel characteristics, ultra-thin strut and polymer-free coating, which have the potential to achieve early re-endotherialization. However, a little is known whether early vascular healing of UPF-SES can be achieved in patients with acute coronary syndrome (ACS).The aim of this study was to evaluate the vascular healing after an implantation of UPF-SES in patients with ACS using optical coherence tomography (OCT) at 3 months after the stent implantation. Methods:From September 2020 and January 2021, a total of 31 consecutive patients presenting with ACS who underwent OCT examinations at the initial percutaneous coronary intervention (PCI) and 3-month follow-up were enrolled in the USUI-ACS study. The endpoints of this study were neointimal strut coverage, malapposition, and mean neointimal hyperplasia (NIH) thickness at 3-month follow-up.Results:Over a mean follow-up of 91 days after the initial PCI, the follow-up OCT was examined. The median percentage of covered struts was 98.4% and malapposed struts 0%, and the mean NIH thickness was 60μm.Conclusions:UPF-SES exhibited an excellent early vascular healing at 3-months in patients with ACS.

show abstract

“…Previous reports have described a high incidence of cardiac events in hemodialysis (HD) patients than in non-HD patients after percutaneous coronary intervention (PCI). [1][2][3] However, little is known about intravascular imaging predictors of cardiac events in patients undergoing HD.…”

Section: Introductionmentioning

confidence: 99%

Impact of calcified nodule on target lesion failure after stent implantation in hemodialysis patients

Matsuhiro

Nakamura

Dohi

et al. 2023

Cathet Cardio Intervent

Self Cite

View full text Add to dashboard Cite

Background: Little is known about intravascular imaging predictors of cardiac events after drug-eluting stent (DES) implantation in hemodialysis (HD) patients. We aimed to reveal the association between calcified nodules (CN) and target lesion failure (TLF) in HD patients after DES implantation.Methods: We enrolled 114 HD patients who underwent DES implantation between October 2016 and October 2020. The patients were divided into a CN group (39%, 44 patients) and a non-CN group (61%, 70 patients). The primary endpoint was the incidence of TLF, including cardiac death, target vessel myocardial infarction, and clinically driven target lesion revascularization.Results: HD duration was longer, and the calcium burden was higher in the CN group than in the non-CN group. Over a median follow-up of 607 days [interquartile range: 349-965 days], the cumulative incidence curve showed that the CN group had a significantly higher incidence of TLF than the non-CN group (31.8% vs. 11.4% within 3 years, p = 0.008). On Fine-Gray sub-distribution hazard model analysis, the CN group was associated with an increased rate of TLF (hazard ratio [HR]: 2.86; 95% confidence interval [CI]: 1.21-6.75, p = 0.016). An in-stent CN was observed in 73% of the lesions with target lesion revascularization in the CN group, whereas no in-stent CN was observed in the non-CN group (p = 0.026).Conclusions: CN was an independent predictor of TLF in patients undergoing HD.In-stent CN was an important cause of TLF after DES implantation in CN lesions in HD patients; therefore, a different strategy should be considered for treating the lesions.

show abstract

Characteristics of abnormal post‐stent optical coherence tomography findings in hemodialysis patients

Cited by 4 publications

References 17 publications

Predictors for the Early Development of Neoatherosclerosis After Newer-generation Drug-eluting Stent Implantation

Predictors for the Early Development of Neoatherosclerosis After Newer-generation Drug-eluting Stent Implantation

Early vascular healing of ultra-thin strut polymer-free sirolimus-eluting stents in acute coronary syndrome: USUI-ACS study

Impact of calcified nodule on target lesion failure after stent implantation in hemodialysis patients

Contact Info

Product

Resources

About