Characteristics, management, and outcomes of patients with left‐sided infective endocarditis complicated by heart failure: a substudy of the ESC‐EORP EURO‐ENDO (European infective endocarditis) registry

Abstract

To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry.

The impact of early surgery on mortality in infective endocarditis complicated by heart failure – How much more data do we need?

“…Of note, among IE patients complicated with HF, 1‐year mortality rates were as high as 29.1% and 58.4% in those who did or did not undergo surgery, respectively, demonstrating the aggressiveness of this condition. Since these data were extracted from registries over a decade ago, the current analysis by Bohbot et al 11 . reinforces these findings and has the advantage of being a contemporary, multicentre analysis focusing only on left‐sided IE.…”

“…In this issue of the Journal, Bohbot et al 11 . explored the characteristics, management and outcomes of left‐sided IE complicated by HF and described the effect of early surgical intervention on mortality rates in these patients.…”

“…7,8 Therefore, consensus recommendations were drawn regarding the need for early surgical interventions in certain high-risk IE cases including haemodynamic instability, heart block, HF, systemic embolization and persistent infection. 9 Of these features, HF was repeatedly shown to represent both a common risk factor, but also a significant sign for early complications and increased mortality and was therefore suggested as an important marker for the need for early surgical In this issue of the Journal, Bohbot et al 11 explored the characteristics, management and outcomes of left-sided IE complicated by HF and described the effect of early surgical intervention on mortality rates in these patients. To do that, they analysed the contemporary, prospective, multicentre European Endocarditis Registry (EURO-ENDO) incorporating more than 3000 IE patients recruited from >40 countries between January 2016 and March 2018.…”

July 2022 at a glance: focus on prognosis, devices and valvular heart disease

“…Because of considerable surgical risk, only about half of patients with HF underwent surgery, which was associated with lower mortality rates. 22 Iron deficiency is a common finding in HF patients and its treatment with ferric carboxymaltose (FCM) infusion may improve symptoms, functional capacity and reduce HF hospitalizations. 23,24 IIISAS was a randomized, single-centre trial with the aim to evaluate if intravenous iron administered about 3 months before transcatheter aortic valve implantation (TAVI) could lead to clinical benefit in patients with severe aortic stenosis and iron deficiency.…”

“…Development of HF was independently associated with higher mortality. Because of considerable surgical risk, only about half of patients with HF underwent surgery, which was associated with lower mortality rates 22 …”