Characteristics and Treatment of Patients Diagnosed With Paradoxical Adipose Hyperplasia After Cryolipolysis: A Case Series and Scoping Review

Cox, Elizabeth A; Nichols, D Spencer; Riklan, Joshua E; Pomputius, Ariel; Mehta, Sonia D.; Mast, Bruce A.; Furnas, Heather; Canales, Francisco L.; Sorice-Virk, Sarah

doi:10.1093/asj/sjac219

Cited by 6 publications

(3 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…26 Case studies describing the occurrence of paradoxical adipose hyperplasia in the treatment area months after cryolipolysis, despite the fact that the prevalence is predicted to be as low as 0.0051%. [27][28][29] MW technology is widely used nowadays, and it is not new in medical applications. It is feasible to target subcutaneous fat cells effectively and safely by carefully controlling the MW frequency.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Use of a microwave device for the treatment of cellulite and localized fat adiposity: a 1‐year follow‐up study

Salsi¹,

Coli²,

Ronconi

et al. 2023

Skin Research and Technology

View full text Add to dashboard Cite

Background The body contour market has grown steadily over the last years, due to the persistent demand for non‐invasive treatments for localized fat adiposities, cellulite, and skin laxity. Materials and Methods The purpose of this observational study was to evaluate the efficacy and safety of a new device delivering microwaves (MWs) energy for unwanted fat and cellulite reduction after a full cycle of treatments and 1 year later. A total of 45 patients with localized adiposity and/or cellulite in different body areas (inner thigh, upper arm, abdomen, culotte de cheval, buttocks), received four treatment sessions, 4 weeks apart. Photographic records and global aesthetic improvement scale (GAIS) score were performed. Results For the treatment of cellulite the average GAIS score passed from 3.65 ± 0.49 at 1‐month follow‐up (1MFU) to 2.7 ± 0.66 at 1‐year follow‐up (1YFU). For the treatment of localized adiposity, the average GAIS score passed from 3.52 ± 0.51 at 1MFU to 2.82 ± 0.88 at 1YFU. No particular red area was detected either during or after the treatment. There was no mention of assessment of pain or side effects. Conclusions The study findings showed that MWs allow for the treatment of cellulite and localized fat adiposity in a safe and effective way, with results lasting over time up to 1 year after the end of the treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Case studies describing the occurrence of paradoxical adipose hyperplasia in the treatment area months after cryolipolysis, despite the fact that the prevalence is predicted to be as low as 0.0051% 27–29 …”

Section: Discussionmentioning

confidence: 99%

Use of a microwave device for the treatment of cellulite and localized fat adiposity: a 1‐year follow‐up study

Salsi¹,

Coli²,

Ronconi

et al. 2023

Skin Research and Technology

View full text Add to dashboard Cite

show abstract

“…9 A recent retrospective case series of 4 patients diagnosed with PAH after cryolipolysis at a large academic medical center calculated the incidence of PAH as 0.67. 26 These kinds of discrepancies and different approaches to defining certain risks complicate the understanding of AEs in cryolipolysis, and thus patients may not have a true understanding of their risks before undergoing treatment.…”

Section: Paradoxical Adipose Hyperplasiamentioning

confidence: 99%

Literature review of adverse events associated with cryolipolysis

Deligonul,

Yousefian,

Gold

2023

J of Cosmetic Dermatology

View full text Add to dashboard Cite

BackgroundCryolipolysis is a noninvasive procedure for localized fat reduction and body contouring. This technique utilizes controlled cooling to induce adipocyte apoptosis without damage to overlying skin and other tissue. Although the procedure was once thought to be relatively harmless, recent studies have shed light on the risks of adverse effects (AEs).AimsThe aim of this article was to review AEs in cryolipolysis as published in clinical data.MethodsA comprehensive search was performed in PubMed, using relevant keywords such as “cryolipolysis,” “CoolSculpting,” “adverse effects,” “complications,” and “side effects” with no set data range. The search was limited to studies published in English. The selected studies encompassed a variety of study designs, including randomized controlled trials, prospective cohort studies, case series, case reports, and reviews.ConclusionsSince its FDA approval in 2010, our understanding of the potential risks and complications associated with cryolipolysis has grown significantly, and shown that the procedure may not be as harmless as once thought. Continued post‐market surveillance of cryolipolysis devices combined with documenting of AE cases help providers better understand the true risks associated with this procedure. As “cryolipolysis” and “CoolSculpting” are often used interchangeably, further research is needed to understand if AEs such as paradoxical adipose hyperplasia (PAH) that occur both inside and outside the United States are CoolSculpting cases or linked to other devices. Additionally, further studies are needed to understand the pathophysiology of such sequelae as PAH, and to better recognize the risks and potential complications associated with cryolipolysis so that we can more accurately inform patients.

show abstract

Effect of adrenaline concentration in tumescence solution on intraoperative hemodynamics of liposuction patients: A randomized triple-blind trial

Abosakaya,

Kohaf,

Elmeligy

et al. 2023

Egyptian Journal of Anaesthesia

View full text Add to dashboard Cite

Characteristics and Treatment of Patients Diagnosed With Paradoxical Adipose Hyperplasia After Cryolipolysis: A Case Series and Scoping Review

Cited by 6 publications

References 28 publications

Use of a microwave device for the treatment of cellulite and localized fat adiposity: a 1‐year follow‐up study

Use of a microwave device for the treatment of cellulite and localized fat adiposity: a 1‐year follow‐up study

Literature review of adverse events associated with cryolipolysis

Effect of adrenaline concentration in tumescence solution on intraoperative hemodynamics of liposuction patients: A randomized triple-blind trial

Contact Info

Product

Resources

About