Characteristics and timing of mortality in children dying in pediatric intensive care: a 5-year experience

Gün, Emrah; Şen, Emine Kübra; Yöndem, Cansu; Gurbanov, Anar; Balaban, Burak; Kahveci, Fevzi; Özen, Hasan; Uçmak, Hacer; Gençay, Ali Genco; Kendirli, Tanıl

doi:10.4266/acc.2022.00395

Cited by 2 publications

(1 citation statement)

References 23 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the same study, multiorgan failure and cardiac diseases were common causes in patients who died early. 30 Another recent study reported sepsis and septic shock as the common cause of early decedents. 31 So, our study findings are in line with the recent literature.…”

Section: Discussionmentioning

confidence: 99%

Descriptive and Clinical Characteristics of Nonsurvivors in a Tertiary Pediatric Intensive Care Unit in Turkey: 6 Years of Experience

Karakaya

Boyraz

Atis

et al. 2023

J Pediatr Intensive Care

View full text Add to dashboard Cite

The objective of this study was to identify the characteristics of nonsurvivors in a pediatric intensive care unit (PICU) in Turkey. This is a retrospective analysis of patients who died in a tertiary PICU over a 6-year period from 2016 to 2021. Data were drawn from electronic medical records and resuscitation notes. Mode of death was categorized as failed cardiopulmonary resuscitation (F-CPR) or brain death. Among the 161 deaths, 136 nonsurvivors were included and 30.1% were younger than 1 year. Severe pneumonia, respiratory failure, and acute respiratory distress syndrome (ARDS) (31.6%) were the most common primary diagnoses. The most common mode of death was F-CPR (86.8%). More than half of the subjects had been admitted from pediatric emergency departments (58.1%), and more than half (53.7%) had died within 7 days in the PICU. Patients admitted from pediatric emergency departments had the lowest frequency of comorbidities (p < 0.001). Severe pneumonia, respiratory failure, and ARDS diagnoses were significantly more frequent in those who died after 7 days (p < 0.001), whereas septicemia, shock, and multiple organ dysfunction were more common among those who died within the first day of PICU admission (p < 0.001). It may be important to note that patients referred from wards are highly likely to have comorbidities, while those referred from pediatric emergency departments may be relatively younger. Additionally, patients with septicemia, shock, or multiple organ dysfunction were more likely to die earlier (within 7 days), especially compared with those with severe pneumonia, respiratory failure, or ARDS.

show abstract

Section: Discussionmentioning

confidence: 99%

Descriptive and Clinical Characteristics of Nonsurvivors in a Tertiary Pediatric Intensive Care Unit in Turkey: 6 Years of Experience

Karakaya

Boyraz

Atis

et al. 2023

J Pediatr Intensive Care

View full text Add to dashboard Cite

show abstract

Association between mortality and critical events within 48 hours of transfer to the pediatric intensive care unit

Liang,

Carey,

Jani

et al. 2023

Front. Pediatr.

View full text Add to dashboard Cite

IntroductionCritical deterioration in hospitalized children, defined as ward to pediatric intensive care unit (PICU) transfer followed by mechanical ventilation (MV) or vasoactive infusion (VI) within 12 h, has been used as a primary metric to evaluate the effectiveness of clinical interventions or quality improvement initiatives. We explore the association between critical events (CEs), i.e., MV or VI events, within the first 48 h of PICU transfer from the ward or emergency department (ED) and in-hospital mortality.MethodsWe conducted a retrospective study of a cohort of PICU transfers from the ward or the ED at two tertiary-care academic hospitals. We determined the association between mortality and occurrence of CEs within 48 h of PICU transfer after adjusting for age, gender, hospital, and prior comorbidities.ResultsExperiencing a CE within 48 h of PICU transfer was associated with an increased risk of mortality [OR 12.40 (95% CI: 8.12–19.23, P < 0.05)]. The increased risk of mortality was highest in the first 12 h [OR 11.32 (95% CI: 7.51–17.15, P < 0.05)] but persisted in the 12–48 h time interval [OR 2.84 (95% CI: 1.40–5.22, P < 0.05)]. Varying levels of risk were observed when considering ED or ward transfers only, when considering different age groups, and when considering individual 12-h time intervals.DiscussionWe demonstrate that occurrence of a CE within 48 h of PICU transfer was associated with mortality after adjusting for confounders. Studies focusing on the impact of quality improvement efforts may benefit from using CEs within 48 h of PICU transfer as an additional evaluation metric, provided these events could have been influenced by the initiative.

show abstract

Characteristics and timing of mortality in children dying in pediatric intensive care: a 5-year experience

Cited by 2 publications

References 23 publications

Descriptive and Clinical Characteristics of Nonsurvivors in a Tertiary Pediatric Intensive Care Unit in Turkey: 6 Years of Experience

Descriptive and Clinical Characteristics of Nonsurvivors in a Tertiary Pediatric Intensive Care Unit in Turkey: 6 Years of Experience

Association between mortality and critical events within 48 hours of transfer to the pediatric intensive care unit

Contact Info

Product

Resources

About