Characteristics and prognosis of patients after resection of nonsmall cell lung carcinoma measuring 2 cm or less in greatest dimension

Abstract

Die verblüffend unterschiedliche Reaktivität einfacher Komplexe des Typs [PnRhX] hängt stark von der Art und der Zahl der Trialkylphosphan‐Liganden (P) sowie den anionischen Liganden X ab: In Konkurrenzexperimenten mit Aldehyden und Methyliodid wird bei Verwendung verschiedener Komplexe selektiv eines von beiden addiert [Gl. (1) und (2)].

Results of surgical treatment for small (2 cm or Under) adenocarcinomas of the lung

“…The multivariate analyses identifi ed an older age, male sex, wedge resection, advanced stage, Noguchi classifi cation C, D, E, or F as independent prognostic factors that adversely affected the overall survival. Okada et al 8 found the pathologic stage, preoperative serum CEA level, and vascular vessel invasion to be signifi cant, independent determinants of survival in patients with a non-small cell lung carcinoma measuring 2 cm or less in diameter. Inoue et al 1 recently reported that an increased preoperative serum CEA level is an independent predictor of a poor prognosis in patients with nonsmall cell lung cancer 2 cm or less in diameter, and the rate of lymph node metastasis was signifi cantly higher in those patients.…”

“…A lobectomy is the standard surgical procedure even for small lung cancers, because some studies have demonstrated progressive disease in 10%-20% of patients with small lung cancers. 4,8 Many reports defi ne small lung cancers as having a maximum diameter of 2 cm or less, [1][2][3][4]8 and since adenocarcinoma has been reported to account for 85%-90% of small peripheral lung cancers, 1-3 in this study we restricted our analysis of small peripheral lung cancers to adenocarcinomas. Postoperatively, 89% of the patients (465) had stage IA disease, while the other 11% had progressive disease.…”

Early Detection of Lung Cancer

“…Anatomical resection (lobectomy or segmentectomy) and nodal dissection remain the optimal procedure for CT-detected cancers, as the risk of nodal metastases for solid lesions is in the order of 20% even below 2 cm of size, and 10% below 1 cm [55,56,57,58]. Evidence is emerging, however, that pure non-solid lesions (GGOs) of 2 cm or less have a negligible risk of metastases and may be treated by non-anatomic sublobar resections [59].…”

How many pathological T1N0M0 non-small cell lung cancers can be completely resected in one segment? Special reference to high-resolution computed tomography findings

“…[2][3][4][5][6][7][8][9] Most authors set "a smaller than 2 cm tumor" as one criterion for selecting segmentectomy 2-5 because T1N0M0 NSCLCs smaller than 2 cm have less frequent metastases to lymph nodes and a better prognosis after lobectomy than those of 2.1-3 cm. [10][11][12][13] In addition, most surgeons believe that a tumor smaller than 2 cm is reasonable to allow for a suffi cient surgical margin for resection of one segment. However, it has not been examined fully whether this tumor size is a reasonable cutoff size for the resection of one segment.…”