Characteristics and prognosis of EGFR mutations in small cell lung cancer patients in the NGS era
Xiaohong Xie,
Guihuan Qiu,
Ziyao Chen
et al.
Abstract:Purpose
Targeted therapy has not been effective for small cell lung cancer (SCLC) patients. Although some studies have reported on EGFR mutations in SCLC, a systematic investigation into the clinical, immunohistochemical, and molecular characteristics and prognosis of EGFR-mutated SCLCs is lacking.
Methods
Fifty-seven SCLC patients underwent next-generation sequencing technology, with 11 in having EGFR mutations (group A) and 46 without (group B). Immunohi… Show more
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