Characteristics and Preliminary Clinical Results of a Cohort of Patients in Santiago, Chile, Undergoing Haploidentical Hematopoietic Cell Transplantation with Post Transplant Cyclophosphamide

Abstract

mortality, compared with PtCy and non-PtCy UCBT. This effect was independent of other relevant variables. The shorter time to neutrophil and platelet engraftment and no increase of aGVHD could explain the decrease in early mortality. The impact of this approach over cGvHD and long-term mortality is uncertain at this moment; nevertheless, we have no evidence of increased relapse in acute leukemia. Although further studies are necessary, dual-PtCy could be an alternative for patients without matched sibling donor.