Characteristics and Outcomes of Percutaneous Biliary Interventions in the United States

Hafezi-Nejad, Nima; Bailey, Christopher R.; Areda, Moustafa Abou; Lafaro, Kelly J.; Liddell, Robert P.; Holly, B.; Weiss, Clifford R.

doi:10.1016/j.jacr.2021.03.010

Cited by 6 publications

(4 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…17,18 The reported incidence of major sepsis after PTBD may be as high as 4%, 3,6 and a five-fold increase in in-hospital mortality was reported when sepsis was accompanied in patients undergoing PBI. 2 Considering that this high incidence of systemic infection after PBI exceeds that after general abdominal surgery, 19 the need for prophylactic antibiotics seems unquestionable. However, no studies have evaluated the effectiveness of prophylactic antibiotics in patients undergoing PBI.…”

Section: Discussionmentioning

confidence: 99%

“…Unlike vascular procedures, which are mostly aseptic, PBI carries a significant risk of infectious complications including ascending cholangitis, pancreatitis, and peritonitis, especially when the procedure requires mechanical agitation of the infected biliary tract 17,18 . The reported incidence of major sepsis after PTBD may be as high as 4%, 3,6 and a five‐fold increase in in‐hospital mortality was reported when sepsis was accompanied in patients undergoing PBI 2 . Considering that this high incidence of systemic infection after PBI exceeds that after general abdominal surgery, 19 the need for prophylactic antibiotics seems unquestionable.…”

Section: Discussionmentioning

confidence: 99%

“…Percutaneous biliary intervention (PBI) is a commonly performed procedure for inadequate bile drainage and biliary leakage 1 . However, PBI may result in infectious complications including major sepsis, 2,3 so the administration of prophylactic antibiotics is required prior to the intervention.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Timing of prophylactic antibiotics administration and suspected systemic infection after percutaneous biliary intervention

Im,

Oh,

Lim

et al. 2023

J Hepato Biliary Pancreat

View full text Add to dashboard Cite

Background/PurposeProphylactic antibiotics administration before percutaneous biliary intervention (PBI) is currently recommended, but the underlying evidence is mostly extrapolated from prophylactic antibiotics before surgery. The aim of this study was to evaluate the impact of prophylactic antibiotics administration timing on the incidence of suspected systemic infection after PBI.MethodsThe incidence of suspected systemic infection after PBI was compared in patients who received prophylactic antibiotics at four different time intervals between antibiotics administration and skin puncture for PBI. Suspected post‐intervention systemic infection was assessed according to predetermined clinical criteria.ResultsThere were 98 (21.6%) suspected systemic infections after 454 PBIs in 404 patients. There were significant differences among the four groups in the incidence of suspected systemic infection after the intervention (p = .020). Fever was the most common sign of suspected systemic infection. Administration of prophylactic antibiotics more than an hour before PBI was identified as an independent risk factor of suspected systemic infection after adjusting for other relevant factors (adjusted odds ratio = 10.54; 95% confidence interval, 1.40–78.86).ConclusionsThe incidence of suspected systemic infection after the PBI was significantly lower when prophylactic antibiotics were administered within an hour before the intervention.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Timing of prophylactic antibiotics administration and suspected systemic infection after percutaneous biliary intervention

Im,

Oh,

Lim

et al. 2023

J Hepato Biliary Pancreat

View full text Add to dashboard Cite

show abstract

“…RASis were also reported to attenuate the fibrosis and improve the prognosis of various cancers [ 13 , 14 ], but not well studied in CCA. In addition, hypertension is the most common comorbidity in CCA patients receiving adjuvant therapies (22.0-73.1%) [ 15 – 20 ]. But up to now, there is still no official guidelines for the usage strategies of anti-hypertensive drugs for patients with CCA and hypertension concurrently.…”

Section: Introductionmentioning

confidence: 99%

Renin-angiotensin system inhibitors improve the survival of cholangiocarcinoma: a propensity score-matched cohort study

Zhu,

Li,

Fang

et al. 2023

BMC Cancer

View full text Add to dashboard Cite

Background Hypertension is a risk factor for cholangiocarcinoma (CCA). The effect of anti-hypertensive drugs on the prognosis of CCA is not clear. Methods This is a retrospective study of 102 patients (56.9% males, median age 66 years) diagnosed with CCA and hypertension concurrently and received radical surgery (R0), with a median follow-up of 36.7 months. Kaplan-Meier analysis, Cox regressions, and propensity score (PS) matching were applied for statistical analysis. Results Results of multivariable cox analysis showed that renin-angiotensin system inhibitors (RASis) usage was a protective factor for progression-free survival (PFS) (hazard ratio [HR] = 0.55, 95% confidence interval [95% CI]: 0.32–0.96) and overall survival (OS) (HR = 0.40, 95% CI: 0.20–0.79), respectively. Calcium channel blockers, diuretics, and β-blockers didn’t show significant associations. The association of RASis usage and PFS and OS was derived by PS matching, with a cohort of 28 RASis users and 56 RASis non-users. The median PFS and OS of RASis users (PFS, 17.6 months (9.2–34.4); OS, 24.8 months (16.5–42.3)) were longer than RASis non-users (PFS, 10.5 months (4.1–24.1); OS, 14.6 months (10.6–28.4)). The 1 year, 2 years, and 3 years’ survival rates of RASis users (89.1%, 77.0%, and 65.5%) were higher than RASis non-users (70.9%, 54.0%, and 40.0%). Conclusions RASis usage improves the survival of patients with CCA and hypertension concurrently.

show abstract

Effectiveness and complication rates of percutaneous transhepatic fluoroscopy-guided management of common bile duct stones: a single-arm meta-analysis

et al. 2023

View full text Add to dashboard Cite

Characteristics and Outcomes of Percutaneous Biliary Interventions in the United States

Cited by 6 publications

References 28 publications

Timing of prophylactic antibiotics administration and suspected systemic infection after percutaneous biliary intervention

Timing of prophylactic antibiotics administration and suspected systemic infection after percutaneous biliary intervention

Renin-angiotensin system inhibitors improve the survival of cholangiocarcinoma: a propensity score-matched cohort study

Effectiveness and complication rates of percutaneous transhepatic fluoroscopy-guided management of common bile duct stones: a single-arm meta-analysis

Contact Info

Product

Resources

About