Characteristics and Outcomes of Full-thickness Macular Hole Repair in Patients Receiving Anti-VEGF Injections for Neovascular Age-related Macular Degeneration

Ringeisen, Alexander L.; Parke, David W.; Dev, Sundeep

doi:10.1097/iio.0000000000000248

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2021

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“…16–18 Commonly, MH occurs in the seventh decade of life and has a female predominance. 10 The age of patients in a previous study on idiopathic MH was 70.3 years, similar to that of 70.1 years in our study. 19 The proportion of women was approximately 70% in that study and 60% in our study.…”

Section: Discussionsupporting

confidence: 89%

“…13 There are several reports on MH formation in eyes with PED after anti-VEGF treatment. 10,25 Mojana et al 5 suggested that changes in PED height after anti-VEGF treatment might contribute to the formation of MH by enhancing the tractional forces. However, in eyes with PED, gradual retinal thinning by RPE dysfunction may contribute to MH formation associated with AMD.…”

Section: Discussionmentioning

confidence: 99%

“…8 Formation of MH might be contributed by the anteroposterior vitreofoveal traction as suggested by Tanner et al 9 The majority of MH occurs as an age-related idiopathic condition. 10 Thus, both MH and AMD are age-related conditions, which become progressively worse with increasing age.…”

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confidence: 99%

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