After completing this course, the reader will be able to:1. Explain the differences in risk and aggression of breast cancer for Hodgkin's lymphoma survivors.2. Describe the difference in breast tumor sites for Hodgkin's lymphoma survivors.3. Use adapted guidelines for surveillance and treatment of these high-risk patients.This article is available for continuing medical education credit at CME.TheOncologist.com. CME CME
ABSTRACTPurpose. To assess breast cancer (BC) risk after Hodgkin's lymphoma (HL) and compare characteristics, risk of second BC, and prognosis of patients with these BCs with patients with first primary BC.Patients and Methods. We considered all 9,620 women with HL recorded in the Surveillance, Epidemiology and End Results dataset in 1973-2007. We calculated age-period standardized incidence ratios of BC. We compared patient, tumor, and treatment characteristics, risk of second BC, and prognosis between patients with BC after HL (n ؍ 316) and patients with other BCs occurring during the same period (n ؍ 450,413) using logistic regression and Cox models adjusted for confounders.Results. HL patients had a 2.