Characteristics and outcome of living kidney donors after donation: A report from Cote d′Ivoire

Abstract

Kidney transplantation from living kidney donors (LKDs) because of its good results represents a good option for the treatment of patients with the end-stage renal disease. Kidney donation is a relatively safe procedure according to several studies. We conducted this cross-sectional study in order to describe the demographic, clinical, and renal outcome of LKD in Côte d'Ivoire. From March to November 2014, LKD residing in Côte d'Ivoire at the time of investigation and having donated the kidney more than one year ago were considered for the study. They were evaluated through a questionnaire. Of the 29 LKD listed in Côte d'Ivoire, only 14 responded to the questionnaire. The mean age at donation was 43.29 ± 9.12 years (27-59) and 10 of the LKD were women. Eight were related to the recipients, and the remaining were spouses. Laparoscopic nephrectomy was performed in nine LKD. The left kidney was harvested in ten cases. The main motivation for donation in all donors was the desire to save a life. At the time of the survey, the average duration after the donation was 4.57 ± 2.56 years (1-8). Only five donors had a regular nephrological follow-up. Hypertension was observed in one donor, seven had significant proteinuria, and six had glomerular filtration rate <60 mL/min but >30 mL/min. Significantly higher proteinuria was noted in donors under 45 years as compared to those over 45 years (0.43 ± 0.17 g/24 h vs. 0.22 ± 0.03 g/24 h, P = 0.01). Our study suggests that renal disease in LKD in Côte d'Ivoire is low after a mean follow-up period of four years. A donor registry is essential to ensure better follow-up of donors in order to detect potential adverse effects of kidney donation in the medium as well as in the long-term.

Adherence Factors Affecting Kidney Transplant Recipient among Patients on Maintenance Haemodialysis in C&#244;te d’Ivoire

“…This result contrasts with a study carried out in Côte d'Ivoire as a prelude to the kidney transplantation project, which identified a large number of potential living donors [17]. To increase the number of effective donors, accurate information and promotion of donation is needed, for, a study carried out in Côte d'Ivoire on the future of the living donors has shown that the risk related to kidney donation is weak after an average of 4 years follow-up [18] as reported in the literature. However, one should note that kidney disease patients are sometimes reluctant to ask for renal donation from a living person.…”

Quality of Life Considerations in 'Caregiver' Renal Donors in Countries with High Living Donor Ratios: A Narrative Review

“…Only 14 living kidney donors were included; 3 complained residual pain and 5 living kidney donors had regular nephrological follow up. Significant proteinuria was noted in 7 LKD, and 6 LKD had GFR<60mL/min [18].…”

Organ Donation and Transplantation in Sub-Saharan Africa: Opportunities and Challenges

“…Ivory Coast implemented the law authorizing organ donation in 2012 [43] and between 2013 and 2015, ten living-related kidney transplantations had been done [44].…”