Characteristics and diagnostic profile of patients seeking dementia care in a memory clinic in Hong Kong

Sheng, Bun; Law, Chun Bon; Yeung, Kwan Mo

doi:10.1017/s104161020800817x

Cited by 35 publications

(51 citation statements)

References 31 publications

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“…In our study, AD was the most common dementia subtype (38.3%), followed by VaD (25.4%); this is consistent with hospital-based studies from different parts of the world [5,9,15,16,35]. Among VaD subtypes, subcortical VaD was the most common and it was present in nearly half of patients, consistent with previous reports [32].…”

Section: Discussionsupporting

confidence: 92%

“…The mean age of dementia patients in developed countries is between 73 and 80 years, in contrast to the 66.3 years reported in our study [5,9,14,15,35]. This finding is probably a reflection of the demographic profile of India.…”

Section: Discussioncontrasting

confidence: 90%

“…The relative proportion of AD versus VaD has varied between studies. The frequency of AD ranges between 50 and 80% in the West and that of VaD ranges from 5.6–8.7% in developed countries [6,7,9] to around 26% in China and Oman [5,15]. More recent hospital-based series from developed countries have reported mixed AD with CVD in one third of patients [7,14].…”

Section: Discussionmentioning

confidence: 99%

“…This approach is possible in specialized memory clinics that have multidisciplinary and experienced teams involved in the comprehensive care of dementia. Studies from memory clinics located in different parts of the world report variability in the clinical profile of dementia and its subtypes [5,9,14,15]. Reasons include methodological differences in diagnosis, sociocultural factors in attitudes towards dementia, and demographic variability.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Subtypes of Dementia: A Study from a Memory Clinic in India

Alladi

Mekala

Chadalawada

et al. 2011

Dement Geriatr Cogn Disord

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Background: The clinical syndrome of dementia consists of several subtypes that are distinct in their etiology, clinical profile, management, and outcome. Limited specialized services are available for dementia patients in India. We report the profile of dementia subtypes from a clinic-based dementia registry in India. Methods: Consecutive dementia patients were investigated with clinical evaluation, neuropsychological tests modified for local use, and brain imaging. Results: In 347 consecutive dementia patients, Alzheimer’s disease was the most common subtype of dementia (38.3%), followed by a high proportion of vascular dementia (25.4%). Frontotemporal dementia syndromes were not uncommon (18.7%). Dementia with Lewy bodies was encountered in 8.9% of the patients, and mixed dementia was found in 8.6%. The mean age of the group at presentation was 66.3 years, nearly a decade younger than in developed countries. The proportion of patients with early-onset dementia was high (49.9%). Conclusions: Our results demonstrate that the clinical profiles of dementia subtypes in a clinic population are influenced by the population’s demographic profile, cardiovascular risk factor burden, sociocultural attitudes about cognitive impairment, and possibly genetic factors.

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Section: Discussionsupporting

confidence: 92%

Section: Discussioncontrasting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Subtypes of Dementia: A Study from a Memory Clinic in India

Alladi

Mekala

Chadalawada

et al. 2011

Dement Geriatr Cogn Disord

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“…Kochunov et al [19] found anatomical differences in the frontal, temporal and parietal gyri between Chinese and English speakers, which might be due to neural plasticity. Compared with English speakers, native Chinese have also been reported to behave differently in psychological and epidemiological studies [20,21,22,23]. Thus, it is reasonable for native Chinese speakers with SCA3 to develop unique cognitive impairments that differ from those of their English-speaking counterparts.…”

Section: Introductionmentioning

confidence: 99%

Cognitive Impairment in Native Chinese with Spinocerebellar Ataxia Type 3

Chen

Hou

et al. 2014

Eur Neurol

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Background: Previous studies have shown cognitive impairment in patients with spinocerebellar ataxia type 3 (SCA3). However, there is a lack of data on Chinese patients with SCA3. Method: We investigated 22 native Chinese with SCA3 and 18 controls matched for age, education as well as mental status. Cognitive assessments were carefully carried out to measure verbal fluency, memory, attention, executive function, visuospatial and visuoconstructive functions. Results: The most common impairments of cognition in native Chinese with SCA3 were disruption of phonemic verbal fluency and frontal executive dysfunction. Deficits in semantic fluency were detected in about 31.8% patients. Impaired visuospatial function and verbal memory were also found in native Chinese with SCA3. The degree of ataxia, CAG repeat length and education were found to correlate with cognitive performance. Multivariate binary logistic regression suggested that an oculomotor disorder and depression are predictors of cognitive impairment. Conclusion: Native Chinese with SCA3 had cognitive impairment of frontal executive function, temporal and parietal functions. An oculomotor disorder might be an index of cognitive dysfunction.

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Reversible Dementias

Philpot¹

2010

Principles and Practice of Geriatric Psychiatry

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Characteristics and diagnostic profile of patients seeking dementia care in a memory clinic in Hong Kong

Abstract: Dementia patients in Hong Kong apparently enjoy a long subclinical period and only seek medical attention at late stages. Local Chinese culture and socioeconomic backgrounds could be the main reasons that underlie these observations.

Cited by 35 publications

References 31 publications

Subtypes of Dementia: A Study from a Memory Clinic in India

Subtypes of Dementia: A Study from a Memory Clinic in India

Cognitive Impairment in Native Chinese with Spinocerebellar Ataxia Type 3

Reversible Dementias

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