Characteristics and application of tick cell lines

Nakao, Ryo

doi:10.7601/mez.70.175

Cited by 1 publication

(1 citation statement)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition to tick colonies, the Tick Cell Biobank was established in 2009, covers 30 collaborating institutes in Asia, Africa, the Americas and Europe, and the cell lines it distributes have become essential auxiliary tools for promotion of tick research (Bell-Sakyi et al, 2018). The cell lines of hard ticks are derived from genera Amblyomma, Dermacentor, Hyalomma, Ixodes, Rhipicephalus and subgenus Boophilus, but there is no cell line of genus Haemaphysalis at present (Nakao, 2019). Some cell lines have been subjected to studies on genomics, biology and physiology, innate immunity, tick-borne pathogens and microbiome.…”

Section: Importance Of Laboratory Colonies Of Ticks As Research Resoumentioning

confidence: 99%

Hard ticks as research resources for vector biology: from genome to whole-body level

Umemiya‐Shirafuji

Fujisaki

Okado

et al. 2019

Jap. J. Sanit. Zool.

View full text Add to dashboard Cite

In the past decades, omics data including genomes, transcriptomes and proteomes of several tick species of medical and veterinary importance have become available as web-based resources. In addition, laboratory colonies and tick cell lines have been established and are now essential tools for the advancement of tick research. Unfortunately, currently, such databases and the biobank of the ticks distributed in Japan are insufficient. To date, available data are from Haemaphysalis longicornis Neumann, 1901, one of major hard tick species in Japan and a vector of various microorganisms that are harmful to human and animals. H. longicornis has been used as an "experimental model of hard tick" for biological and physiological studies and for validation of effectiveness of insecticides or acaricides in research institutions. The parthenogenetic tick is used as research material because it can be stably supplied. This mini-review provides a concise overview of recent advances of omics approaches in tick research. The importance of laboratory colonies of ticks and the prospect of tick research in Japan are also discussed.

show abstract

Section: Importance Of Laboratory Colonies Of Ticks As Research Resoumentioning

confidence: 99%