2016
DOI: 10.15562/bmj.v5i1.325
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Characteristic of Gastric Perforation Type and The Histopathology at Haji Adam Malik General Hospital Medan-Indonesia

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Cited by 6 publications
(6 citation statements)
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“…This is in accordance with the previous theory which states that gastric perforation is rare under 40 years of age, with a peak incidence at 55-65 years of age. 10 It has also been reported that age more than 60 years was the main risk factor affecting outcome, postoperative mortality in the elderly was 3 to 5 times higher. 2 Patients older than 65 years were associated with a higher mortality rate when compared to younger patients (37.7% vs 1.4%).…”
Section: Resultsmentioning
confidence: 95%
“…This is in accordance with the previous theory which states that gastric perforation is rare under 40 years of age, with a peak incidence at 55-65 years of age. 10 It has also been reported that age more than 60 years was the main risk factor affecting outcome, postoperative mortality in the elderly was 3 to 5 times higher. 2 Patients older than 65 years were associated with a higher mortality rate when compared to younger patients (37.7% vs 1.4%).…”
Section: Resultsmentioning
confidence: 95%
“…3 As with NSAIDs, disruption of the balance of the lining of the gastric mucosa occurs in several ways; decreased mucus production as a factor in gastric protection, disruption of gastric acid production, and inhibition of COX-1, which causes vasoconstriction so that vascularity is not optimal which can cause necrosis of epithelial cells. 6 Meanwhile, based on surgery reports, the perforations are mostly located in 1-5 cm prepylorus. According to its anatomical location, the stomach is divided into several parts, ranging from cardia, fundus, corpus, antrum, and pylorus.…”
Section: Discussionmentioning
confidence: 99%
“…A study by Asefa and Geyesus 16 demonstrated history of smoking in 82.8% of their study population. Kamsir et al 17 provided definite conclusion regarding the relation between alcohol consumption and peptic ulcer perforation. Doll et al 18 and Svanes et al 9 have implicated in their respective studies that smoking is not only involved in the pathogenesis of peptic perforation and PUD but also that smokers have been found to have ulcers more frequently than nonsmokers.…”
Section: Relation With Alcohol/smokingmentioning
confidence: 96%