Characteristic Clinical Features and Survival in Cats with Symptomatic Hypertrophic Cardiomyopathy

Kang, Min Hee; Min, Sa Hee; Kim, Seung-Gon; Lee, Chang Min; Park, Hee Myung

doi:10.12729/jbr.2015.16.4.152

Cited by 4 publications

(6 citation statements)

References 19 publications

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“…Antiviral therapy is of particular importance in this context. If possible, this should be initiated within 72 hours of the appearance of the skin symptoms or within 48 hours of the manifestation of the characteristic skin vesicles [1,6,9,14]. Four different agents are available, which differ in their antiviral potency and also in their mode of administration.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Herpes Zoster Ophthalmicus: A Painful Dermatomal Rash of Both Eyes in A 4 Years-Old Child

Bittmann¹

2023

AJBSR

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Zoster ophthalmicus is caused by reactivation of varicella zoster viruses, which belong to the group of herpes viruses. The symptoms and complaints, such as a dermatomal rash in the forehead area and painful inflammation of all tissues in the anterior and, less commonly, posterior ocular structures, can be very severe. Diagnosis is based on the characteristic findings in the anterior ocular structures associated with zoster dermatitis of the 1st trigeminal branch (V1). We present an interesting case of a 4 years-old boy with bilateral herpes zoster ophthalmicus with a bridging connection between both eyes. 14 to 16 days, possibly as long as 28 days after passive immunization. Herpes zoster symptoms can vary widely. For example, the disease may be mild and cause only itching. On the other hand, shingles is often accompanied by considerable distress, and even light touch can cause considerable pain. The disease usually presents initially with nonspecific symptoms such as malaise, headache, pain in the limbs, and paresthesia's, often followed by a phase of itchy exanthema and fever. Characteristic vesicular skin lesions also occur in herpes zoster. Their localization depends on the supply area of the affected nerves. In many cases, the skin vesicles initially develop in the trunk area and may spread from there to other parts of the body, including the hairy scalp and mucous membranes. Usually, only one dermatome is affected (zoster segmentalis); however, overlapping dermatome involvement is also possible. However, crossing the midline of the body is a rarity (zoster duplex). Very rarely, several skin segments are also affected asymmetrically on both sides of the body. Pain, sensory disturbance and itching often occur several days before the skin symptoms.

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Section: Discussionmentioning

confidence: 99%

Bilateral Herpes Zoster Ophthalmicus: A Painful Dermatomal Rash of Both Eyes in A 4 Years-Old Child

Bittmann¹

2023

AJBSR

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“…ATE, kedilerde kardiyomyopatiler sonucu şekillenen olukça öldürücü ve sessiz seyirli yaygın bir sekel olarak tanımlanmaktadır (Dwyer, 2015;Kang ve ark., 2015;Payne ve ark., 2013;Rush ve ark., 2002;Smith ve Tobias, 2004) . Tipik olarak ATE'li kedilerde; şiddetli ağrıyla karakterize bir ya da daha fazla ekstremitede fonksiyon kaybı, vücut ısısında düşme, soğuk ekstremiteler ve hipokinetik femoral nabız belirlenmektedir (Kang, 2015;Laste ve Harpster, 1995 ark., 1988;Sewell ve ark., 1984). Daha büyük thrombositler metabolik ve enzimatik olarak daha aktif olmakta ve bu durum artmış thrombüs oluşum riskini göstermektedir (Martin ve ark., 1983).…”

Section: Tartışma Ve Sonuçunclassified

“…Rush ve ark., 2002;Smith ve Tobias, 2004) . Tipik olarak ATE'li kedilerde; şiddetli ağrıyla karakterize bir ya da daha fazla ekstremitede fonksiyon kaybı, vücut ısısında düşme, soğuk ekstremiteler ve hipokinetik femoral nabız belirlenmektedir (Kang, 2015;Laste ve Harpster, 1995). Sunulan çalışmada bu klinik bulguları taşıyan ATE'li, erken yorulma şikayeti bulunan ATE'siz HCM'li kediler çalışmaya dahil edilmiştir.…”

Section: Introductionunclassified

Hipertrofik Kardiyomyopatili Kedilerde Trombosit ve Ortalama Trombosit Hacmi Düzeyleri Erken Emboli Oluşumunu Belirlemede Kullanılabilir mi?

Çolakoğlu

Alihosseini²,

Haydardedeoğlu

2018

Harran Üniversitesi Veteriner Fakültesi Dergisi

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Özet: Hipertrofik kardiyomyopati (HCM) kedilerin sıklıkla rapor edilen kalp hastalığıdır. Arterial thromboembolizm (ATE) ise thrombüs fragmentlerinin arteriyal dolaşıma girerek damarlarda obstrüksiyon yaratması sonucu ilişkili klinik belirtilerin ortaya çıkması olarak tanımlanmaktadır. Bu çalışmada; ATE'in eşlik ettiği HCM'li kedilerde, ATE'in bulunmadığı HCM'li kedilerle karşılaştırıldığında artmış koagülasyon aktivitesi (düşük trombosit, yüksek MPV düzeyleri) ile ilgili hipotez değerlendirilmiştir. Çalışma çeşitli yaş ve ırklardaki 25 kedi ile gerçekleştirildi. HCM teşhisinde; sağ parasternal kısa eksende sol ventriküler konsantrik hipertrofi ve sol ventriküler duvar kalınlığı (LVWd ≥6 mm) kriterleri baz alındı. Sağ kısa eksende artmış sol atrium/aort oranı (LA/Ao > 2 mm) belirlendi. Diğer Ekokardiyografik değerlendirmeler için sağ parasternal uzun eksen (sağ PLAX) ve M mod kullanıldı. Çalışmada hastalar (n:25); grup 1 (HCM+ATE; n:9) ve grup 2 (HCM; n: 16) olarak sınıflandırıldı. Grup 1'de trombosit (PLT) ortalamaları grup 2 ile karşılaştırıldığında daha düşük olmasına rağmen gruplar arasında istatistiki farklılığa rastlanmadı (p < 0,05). Ortalama trombosit hacmi (MPV) ortalamaları ise Grup 1'de grup 2'ye göre daha yüksek olmasına rağmen gruplar arasında istatistiki olarak fark saptanmadı. Sonuç olarak; her ne kadar ATE'nin eşlik ettiği HCM'li kedilerde artmış hiperkoagülatif durumun göstergesi olan daha düşük PLT ve daha yüksek MPV düzeyleri bulunduysa da, bu parametrelerin erken thrombüs oluşumunu ortaya koymadaki kullanılabilirliğini belirlemek için daha geniş olgu sayılı prospektif çalışmalara ihtiyaç duyulmaktadır.

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“…The result of this study showed that the plasma ALT concentration was increased in HCM cats affected with ATE compared to those without ATE. An increase of plasma ALT concentration in the HCM group may be secondary to muscle damage or liver injury in cats affected with ATE (Kang et al, 2015).…”

Section: Blood Chemistry Profile Valuesmentioning

confidence: 97%

Assessment of left atrial function in feline hypertrophic cardiomyopathy by using two dimensional speckle tracking echocardiography

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Hypertrophic cardiomyopathy (HCM) is one of the most common myocardial diseases in cats. The left atrial (LA) function plays an essential role in compensatory mechanism of left ventricle with diastolic dysfunction to maintain cardiac output in cats affected with HCM. Nowadays, there are several echocardiographic techniques used to evaluate the left atrial function; however, each technique has limitations. To overcome the limitations, two-dimensional speckle tracking echocardiography (2D-STE) is a novel technique for assessment the LA function. To date, no study focusing on assessment of the left atrial function by 2D-STE in feline HCM has been reported. The objective of this study was to evaluate changes in LA function in HCM cats compared to normal cats by using 2D-STE. Twenty healthy control cats and seventeen client-owned cats affected with HCM were included in this study. The intra-observer and inter-observer measurement variability of peak atrial longitudinal strain (PALS) were 4.17% and 14%, respectively. The mean value and standard deviation of PALS in the HCM group (13.16 ? 8.64%) was lower than those of the control group (28.54 ?10.31%) (p < 0.001). The atrial longitudinal strain of septal and lateral regions was significantly reduced in the HCM group compared to the normal group. The atrial longitudinal strain was lowest at the LA roof region. The PALS correlated with the percentage of fractional shortening of the LA (LA-FS) (r=0.538, p=0.001), the percentage of the LA ejection fraction (LA-EF) (r =0.797, p<0.001), and the LA fractional area change (FAC) (r =0.746, p<0.001).� In conclusion, the PALS can be used to evaluate changes in LA function in HCM cats. It is a reproducibility method for assessing the LA function in cats affected with HCM.

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Characteristic Clinical Features and Survival in Cats with Symptomatic Hypertrophic Cardiomyopathy

Cited by 4 publications

References 19 publications

Bilateral Herpes Zoster Ophthalmicus: A Painful Dermatomal Rash of Both Eyes in A 4 Years-Old Child

Bilateral Herpes Zoster Ophthalmicus: A Painful Dermatomal Rash of Both Eyes in A 4 Years-Old Child

Hipertrofik Kardiyomyopatili Kedilerde Trombosit ve Ortalama Trombosit Hacmi Düzeyleri Erken Emboli Oluşumunu Belirlemede Kullanılabilir mi?

Assessment of left atrial function in feline hypertrophic cardiomyopathy by using two dimensional speckle tracking echocardiography

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