Characteristic changes of saliva and taste in burning mouth syndrome patients

Abstract

BMS patients showed lower salivary flow and higher salivary spinnability. These results together with decreased SIgA amount, suggest that BMS may be relevant to the deterioration of salivary condition, which could in turn affect taste function. Furthermore, the lower antioxidant capacity in patient's serum suggests that it can serve as a diagnostic tool for BMS.

A case‐control evaluation of fungiform papillae density in burning mouth syndrome

“…The finding that the BMS population in our study exhibited increased sensitivity to taste compared with controls (hypergeusia) is surprising. A number of other studies in the literature have reported decreased sensitivity to taste stimulation on the anterior tongue in BMS patients compared with controls . Instead, we observed increased taste sensitivity for quinine on the anterior tongue, as well as for all four taste stimuli when sampled whole mouth.…”

Taste function assessed by electrogustometry in burning mouth syndrome: a case–control study

“…Taste dysfunction in iBMS patients has previously been assessed by whole‐mouth taste evaluation (Formaker and Frank, ; Hershkovich and Nagler, ; Just et al , ; Imura et al , ). Topical tastant testing in iBMS patients (Femiano et al , ; Eliav et al , ; Siviero et al , ) allows localized testing of the different taste papillae.…”

“…Electrical taste stimulation enables selective thresholds recordings (Miller et al , ) and gives a more accurate evaluation of taste sensitivity in the different taste bud fields than chemogustometry ( i.e., excluding olfactory stimulation) in iBMS patients (Eliav et al , ; Just et al , ; Nasri‐Heir et al , ). Although EGMt do not seem to be related to basal and stimulated saliva flow rates (Negoro et al , ), we gave careful attention to saliva secretion assessment within the study sample because subjective dry mouth is commonly evoked in 46–70% of iBMS patients and BSFR is often lower in iBMS patients compared to healthy controls (Imura et al , ). BSFR analyses revealed similar higher than 0.05 ml min −1 BSFR in iBMS and paired controls, which is in accordance with previous studies pertaining to salivary secretion in iBMS (Hershkovich and Nagler, ; Granot and Nagler, ; de Moura et al , ; Borelli et al , ) and confirms that the study sample did not suffer from asialia.…”

“…Gustatory complaints including bitter or metallic phantom tastes and dysgeusia may concern more than half of iBMS patients (Grushka, ; Grushka and Sessle, ) and have been suggested to have a negative influence on oral health‐related quality of life of iBMS patients (Braud and Boucher, ). Taste dysfunction including impaired taste perception (Formaker and Frank, ; Nagler and Hershkovich, ; Eliav et al , ; Just et al , ; Siviero et al , ; Nasri‐Heir et al , ; Imura et al , ) may finally affect more than one‐third of iBMS patients (Formaker et al , ) and could depend on the onset of the burning sensation (Nasri‐Heir et al , ).…”

Burning Mouth Syndrome –Latest update

“…The attempt to treat xerostomia with urea 10% topically failed to improve saliva flow and taste, olfactory, and somesthetic thresholds 40 . Unstimulated saliva flow rates were shown to drop significantly only in BMS patients [41][42][43] , though scintillography of salivary glands did not evince any functional loss in either healthy or hyposalivation patients 41 .…”