Characterisation of porcine epidemic diarrhea virus isolates during the 2014–2015 outbreak in the Philippines

Garcia, Gemerlyn G.; Aquino, Mark Arman D; Balbin, Michelle M.; Belotindos, Lawrence P; Supnet, Jonathan G; Mingala, Claro N.

doi:10.1007/s13337-018-0470-4

Cited by 6 publications

(4 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In May 2013, PED was first reported in Iowa State in the USA, and afterwards rapidly spread to the main pork product states within a year [9,10]. Thereafter, diarrhea outbreaks caused by variant PEDVs appeared in other Asian countries (Thailand, South Korea, Vietnam, and Philippines) [11][12][13][14], America (Canada, Mexico, etc) [15,16], and European countries (Austria, Ukraine, Belgium, Germany, etc) [17,18].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and phylogenetic analysis of porcine diarrhea associated viruses in southern China from 2012 to 2018

Zhang

Luo

et al. 2019

BMC Vet Res

View full text Add to dashboard Cite

BackgroundIn China, large-scale outbreaks of severe diarrhea caused by viruses have occurred in pigs since late 2010. To investigate the prevalence and genetic evolution of diarrhea-associated viruses responsible for the outbreaks, a total of 2987 field diarrheal samples collected from 168 pig farms in five provinces in Southern China during 2012–2018 were tested.ResultsPorcine epidemic diarrhea virus (PEDV) was most frequently detected virus with prevalence rates between 50.21 and 62.10% in samples, and 96.43% (162/168) in premises, respectively. Porcine deltacoronavirus (PDCoV) was the second prevalent virus with prevalence rates ranging from 19.62 to 29.19% in samples, and 70.24% (118/168) in premises, respectively. Both transmissible gastroenteritis virus (TGEV) and porcine rotavirus (PoRV) were detected at low prevalence rates of < 3% in samples and 10.12% in premises. In this study, we identified a newly emerged swine acute diarrhea syndrome coronavirus (SADS-CoV) in diarrheal samples of piglets from Fujian province in Southern China, and the prevalence rate of SADS-CoV was 10.29% (7/68). Co-infections of these diarrhea-associated viruses were common. The most frequent co-infection was PEDV with PDCoV, with an average detection rate of 12.72% (380/2987, ranging from 8.26–17.33%). Phylogenetic analysis revealed that PEDVs circulating in Southern China during the last 7 years were clustered with the variant strains of PEDV in genotype IIa. The most frequent mutations were present in the collagenase equivalent (COE) and epitope regions of the spike gene of the PEDVs currently circulating in the field. Genetic relationships of PDCoVs were closely related with Chinese strains, other than those present in the USA, South Korea, Thailand and Lao’s public.ConclusionsThe findings of this study indicated that variant PEDV, PDCoV, and SADS-CoV were leading etiologic agents of porcine diarrhea, and either mono-infections or co-infections of pathogenic enteric CoVs were common in pigs in Southern China during 2012–2018. Thus, significant attention should be paid in order to effectively prevent and control porcine viral diarrhea.

show abstract

Section: Introductionmentioning

confidence: 99%

Prevalence and phylogenetic analysis of porcine diarrhea associated viruses in southern China from 2012 to 2018

Zhang

Luo

et al. 2019

BMC Vet Res

View full text Add to dashboard Cite

show abstract

“… 2018 ; Garcia et al. 2018 ), North America (Canada, Mexico) (Ojkic et al. 2015 ; Trujillo-Ortega et al.…”

Section: Occurrence and Epidemiologymentioning

confidence: 99%

Swine coronaviruses (SCoVs) and their emerging threats to swine population, inter-species transmission, exploring the susceptibility of pigs for SARS-CoV-2 and zoonotic concerns

Thakor

Dinesh

Manikandan

et al. 2022

Veterinary Quarterly

View full text Add to dashboard Cite

Swine coronaviruses (SCoVs) are one of the most devastating pathogens affecting the livelihoods of farmers and swine industry across the world. These include transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine respiratory coronavirus (PRCV), porcine hemagglutinating encephalomyelitis virus (PHEV), swine acute diarrhea syndrome coronavirus (SADS-CoV), and porcine delta coronavirus (PDCoV). Coronaviruses infect a wide variety of animal species and humans because these are having single stranded-RNA that accounts for high mutation rates and thus could break the species barrier. The gastrointestinal, cardiovascular, and nervous systems are the primary organ systems affected by SCoVs. Infection is very common in piglets compared to adult swine causing high mortality in the former. Bat is implicated to be the origin of all CoVs affecting animals and humans. Since pig is the only domestic animal in which CoVs cause a wide range of diseases; new coronaviruses with high zoonotic potential could likely emerge in the future as observed in the past. The recently emerged severe acute respiratory syndrome coronavirus virus-2 (SARS-CoV-2), causing COVID-19 pandemic in humans, has been implicated to have animal origin, also reported from few animal species, though its zoonotic concerns are still under investigation. This review discusses SCoVs and their epidemiology, virology, evolution, pathology, wildlife reservoirs, interspecies transmission, spill-over events and highlighting their emerging threats to swine population. The role of pigs amid ongoing SARS-CoV-2 pandemic will also be discussed. A thorough investigation should be conducted to rule out zoonotic potential of SCoVs and to design appropriate strategies for their prevention and control.

show abstract

“…Killed virus vaccine induced the higher antibody (IgA and IgG) levels than live virus vaccine particularly in sow's colostrum, sow's sera and piglets sera after suckling (Paudel et al., 2014). In Japan, live attenuated virus is used since 1997 (Usami, Yamaguchi, & Kumanomido, 1998) and oral vaccination started in South Korea and Philippines, since 2004 and 2011 respectively (Garcia et al., 2018; Park et al., 2018). As new virulent strains are circulating, trials for more effective vaccine are undergoing using swine‐poxvirus‐based vaccines designed to express the A epitope of the spike protein (Yuan, Lin, Li, He, & Fan, 2017).…”

Section: Epidemiology Of Farm Animals’ Coronavirusesmentioning

confidence: 99%

Coronaviruses in farm animals: Epidemiology and public health implications

Khbou

Jedidi

Zaafouri

et al. 2020

Veterinary Medicine & Sci

View full text Add to dashboard Cite

Coronaviruses (CoVs) are documented in a wide range of animal species, including terrestrial and aquatic, domestic and wild. The geographic distribution of animal CoVs is worldwide and prevalences were reported in several countries across the five continents. The viruses are known to cause mainly gastrointestinal and respiratory diseases with different severity levels. In certain cases, CoV infections are responsible of huge economic losses associated or not to highly public health impact. Despite being enveloped, CoVs are relatively resistant pathogens in the environment. Coronaviruses are characterized by a high mutation and recombination rate, which makes host jumping and cross‐species transmission easy. In fact, increasing contact between different animal species fosters cross‐species transmission, while agriculture intensification, animal trade and herd management are key drivers at the human‐animal interface. If contacts with wild animals are still limited, humans have much more contact with farm animals, during breeding, transport, slaughter and food process, making CoVs a persistent threat to both humans and animals. A global network should be established for the surveillance and monitoring of animal CoVs.

show abstract

Characterisation of porcine epidemic diarrhea virus isolates during the 2014–2015 outbreak in the Philippines

Cited by 6 publications

References 42 publications

Prevalence and phylogenetic analysis of porcine diarrhea associated viruses in southern China from 2012 to 2018

Prevalence and phylogenetic analysis of porcine diarrhea associated viruses in southern China from 2012 to 2018

Swine coronaviruses (SCoVs) and their emerging threats to swine population, inter-species transmission, exploring the susceptibility of pigs for SARS-CoV-2 and zoonotic concerns

Coronaviruses in farm animals: Epidemiology and public health implications

Contact Info

Product

Resources

About