Characterisation of interaction between food colourant allura red AC and human serum albumin: Multispectroscopic analyses and docking simulations

Wu, Di; Yan, Jin; Wang, Jing; Wang, Qing; Li, Hui

doi:10.1016/j.foodchem.2014.08.088

Cited by 82 publications

(53 citation statements)

References 32 publications

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“…Furthermore, new toxicity concerns have arisen in several colorants due to their ability to bind to human serum albumin. This was reported in Sunset Yellow (Kus and Eroglu, 2015), Tartrazine (Pan et al, 2011), Azorubine (Basu and Kumar 2014a;Datta et al, 2013), Allura Red (Wang et al, 2014;Wu et al, 2015a) and Patent Blue (Tellier et al, 2012). Hypersensitivity reactions have also been reported to become more frequent with new indications of the dyes, e.g.…”

Section: Resultsmentioning

confidence: 86%

Health safety issues of synthetic food colorants

Amchová

Kotolová

Rudá-Kučerová

2015

Regulatory Toxicology and Pharmacology

421

187

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Section: Resultsmentioning

confidence: 86%

Health safety issues of synthetic food colorants

Amchová

Kotolová

Rudá-Kučerová

2015

Regulatory Toxicology and Pharmacology

421

187

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“…It uses the ultraviolet and visible light range of the electromagnetic spectrum. It can be used for quantitative and qualitative analyses of coloured organic compounds (Buchweitz et al, 1979;Zsila et al, 2003;Bukhari et al, 2009;Wu et al, 2015). The quantitative analysis is based on the "BeerLambert" principle which relates light absorbance of substances to their concentrations; provided that the light path and molar absorptivity remain constant (Swinehart, 1962).…”

Section: Ultraviolet/visible (Uv/vis) Spectroscopymentioning

confidence: 99%

Characterization of Copper–Cobalt Ores and Quantification of Cu²⁺, Co²⁺, Co³⁺, and Fe³⁺ in Aqueous Leachates Using UV/Visible Spectrophotometry

Kime

Makgoale

2016

Chemical Engineering Communications

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UV/Vis spectroscopy was used to determine qualitatively and quantitatively Cu 2+ , Co 2+ , Co 3+ and Fe 3+ in oxidised Cu-Co ore leachates. The mineralogical and chemical characteristics of the three oxidised Cu-Co ore samples considered were determined using FT-IR, XRD, SEM-EDS and XRF. The results showed that Cu and Co in the samples were in the form of carrollite (Co 2 CuS 4 ), malachite (Cu 2 CO 3 (OH) 2 and heterogenite (CoO(OH)). The samples contained (2.73%Cu and 0.19%Co), (2.82%Cu and 0.07%Co) and (0.03%Cu and 0.05%Co), respectively. Gangues were mainly constituted of quartz, goethite and hematite. The UV/Vis results indicated that the wavelengths of absorbance of the metal ions in dilute EDTA aqueous solution (pH≈3.5)were Fe 3+ (293 nm), Cu 2+ (821 nm), Co 3+ (344 nm) and Co 2+ (512 nm). The molar concentrations of the metal ions obtained using the UV/vis method compared well with results obtained using the AAS method. UV/vis spectroscopy was also used to monitor the conversion of Co 3+ into Co 2+ using different reducing agents. The results showed that the molar concentration of Co 2+ in the aqueous solutions increased with addition of reducing agents, of about 80.95% (copper foil), 61.22% (ferrous sulphate) and 20.35% (sodium sulphite) respectively.2

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“…As the common edible colorant, sunset yellow (SY) and allura red (AR) have strong genetic toxicity [8,9,10]. It is found that AR has potential behavioral effects on humans and animals and it will increase hyperactivity of children [11,12,13]. Similarly, SY shows negative effects on the cellular immunity [14].…”

Section: Introductionmentioning

confidence: 99%

A Novel Preparation Method of Two Polymer Dyes with Low Cytotoxicity

Zhang

Cui

et al. 2017

Materials

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A new preparation method of polymer dyes was developed to improve both the grafting degree of the azo dyes onto O-carboxymethyl chitosan (OMCS) and the water solubility of prepared polymer dyes. Firstly, the coupling compound of two azo edible colorants, sunset yellow (SY) and allura red (AR), was grafted onto OMCS, and then coupled with their diazonium salt. The chemical structure of prepared polymer dyes was determined by Fourier transform-infrared spectroscopy and 1H-NMR, and the results showed that the two azo dyes were successfully grafted onto OMCS. The grafting degree onto OMCS and the water solubility of polymer dyes were tested, and the results showed that they were both improved as expected. The UV-vis spectra analysis results showed that the prepared polymer dyes showed similar color performance with the original azo dyes. Eventually, the cytotoxicity of prepared polymer dyes was tested and compared with the original azo dyes by a cytotoxicity test on human liver cell lines LO2, and the results showed that their grafting onto OMCS significantly reduced the cytotoxicity.

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Characterisation of interaction between food colourant allura red AC and human serum albumin: Multispectroscopic analyses and docking simulations

Cited by 82 publications

References 32 publications

Health safety issues of synthetic food colorants

Health safety issues of synthetic food colorants

Characterization of Copper–Cobalt Ores and Quantification of Cu²⁺, Co²⁺, Co³⁺, and Fe³⁺ in Aqueous Leachates Using UV/Visible Spectrophotometry

A Novel Preparation Method of Two Polymer Dyes with Low Cytotoxicity

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Characterisation of interaction between food colourant allura red AC and human serum albumin: Multispectroscopic analyses and docking simulations

Cited by 82 publications

References 32 publications

Health safety issues of synthetic food colorants

Health safety issues of synthetic food colorants

Characterization of Copper–Cobalt Ores and Quantification of Cu2+, Co2+, Co3+, and Fe3+ in Aqueous Leachates Using UV/Visible Spectrophotometry

A Novel Preparation Method of Two Polymer Dyes with Low Cytotoxicity

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Characterization of Copper–Cobalt Ores and Quantification of Cu²⁺, Co²⁺, Co³⁺, and Fe³⁺ in Aqueous Leachates Using UV/Visible Spectrophotometry