Characterisation of Drug-Related Problems and Associated Factors at a Clinical Pharmacist Service-Naïve Hospital in Northern Sweden

Peterson, Cecilia; Gustafsson, Maria

doi:10.1007/s40801-017-0108-7

Cited by 53 publications

(71 citation statements)

References 34 publications

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“…e difference could be attributed to differences in training levels of prescribers, availability of support systems, and composition of the health care team in these hospitals. Nonetheless, similar prevalence rates (66-75%) were also reported in different studies [20,[27][28][29][30]. e most frequently encountered DRPs were inappropriate dosing (high and low dose) followed by needs additional drug therapy and nonadherence to the prescribed medications.…”

Section: Discussionsupporting

confidence: 74%

Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia

Yismaw

Adam

Engidawork

2020

Journal of Oncology

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Background. Even though medications play a major role in the cure, palliation, and inhibition of disease, they also expose patients to drug-related problems. Drug-related problems are frequent and may result in reduced quality of life, morbidity, and mortality.Objectives.e study was aimed to identify, characterize, and resolve drug-related problems in the Pediatric Hematology/ Oncology ward of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods. A prospective observational study was conducted from 25 June to 25 October 2018 to assess DRPs on patients admitted at the pediatric hematology/oncology ward of Tikur Anbessa Specialized Hospital, which is the highest level governmental tertiary care hospital in Ethiopia. Data were obtained from patients' medical charts, physicians, patients/caregivers, pharmacists, and nurses. All the collected data were entered and analyzed using the Statistical Package for the Social Sciences version 25e. Descriptive statistics were used to represent the data. Results. Among the total 156 participants, DRPs were identified in 68.6% of the study subjects. Dosing problems which include dosage too low and high were the top ranking (39.3%) of all DRPs followed by needs additional therapy (27.2%) and nonadherence (14.0%). Systemic anti-infectives were the most common class of drugs involved in DRPs. Trimethoprim-sulfamethoxazole, methotrexate, vincristine, ondansetron, and metoclopramide were frequently involved in DRPs. e addition of drugs and change in drug dose were the two most proposed intervention types. Among the proposed interventions, 223 (92.15%) were fully accepted, 9 (3.72%) partially accepted, and 10 (4.13%) not accepted. Conclusion. DRPs are common among Pediatric Hematology/ Oncology ward patients. e hospital should develop a pediatric dosing chart for the commonly prescribed medications to prevent drug-related morbidity and mortality. e integration of clinical pharmacists can mitigate risks associated with DRPs.

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Section: Discussionsupporting

confidence: 74%

Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia

Yismaw

Adam

Engidawork

2020

Journal of Oncology

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“…The analysis of the medication profile of the participants revealed that drugs belonging to the ATC groups "Alimentary tract and metabolism", "Cardiovascular system", and "Nervous system" were the most prescribed drugs. These groups of drugs are frequently associated to an increased prevalence of suffering from drug-related problems [26][27][28].…”

Section: Discussionmentioning

confidence: 99%

Daily Medication Management and Adherence in the Polymedicated Elderly: A Cross-Sectional Study in Portugal

Gomes

Plácido

Mó

et al. 2019

IJERPH

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The presence of age-related comorbidities prone elderly patients to the phenomenon of polypharmacy and consequently to a higher risk of nonadherence. Thus, this paper aims to characterize the medication consumption profile and explore the relationship of beliefs and daily medication management on medication adherence by home-dwelling polymedicated elderly people. A questionnaire on adherence, managing, and beliefs of medicines was applied to polymedicated patients with ≥65 years old, in primary care centers of the central region of Portugal. Of the 1089 participants, 47.7% were considered nonadherent. Forgetfulness (38.8%), difficulties in managing medication (14.3%), concerns with side effects (10.7%), and the price of medication (9.2%) were pointed as relevant medication nonadherence-related factors. It was observed that patients who had difficulties managing medicines, common forgetfulness, concerns with side effects, doubting the need for the medication, considered prices expensive, and had a lack of trust for some medicines had a higher risk of being nonadherent. This study provides relevant information concerning the daily routine and management of medicines that can be useful to the development of educational strategies to promote health literacy and improve medication adherence in polymedicated home-dwelling elderly.

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“…15 However, the reported findings in our study are considered relatively higher in comparison with previous studies which reported 1.29, 1.53 and 1.93 DRPs per patient, respectively. 6,13,21 This shows that the frequency and type of identified DRPs may vary according to the setting. Accordingly, this variation may postulate some…”

Section: In Ward Managementmentioning

confidence: 93%

“…5 DRPs regarding the choice and use of drugs including interactions are relatively common among hospitalised patients which if not managed correctly may result in unwanted clinical and economic consequences. 6 Indeed, within various clinical specialities, the involvement of clinical pharmacists in patient care was found to positively enhance the efficiency of the overall process through providing medication reconciliation services to minimise the incidence and reoccurrence of DRPs and related consequences. 7 Moreover, the inclusion of clinical pharmacists in dispensing medical practices in Scotland, in the pharmaceutical care of patients has helped to optimise the impact of medication treatment programs in both the quantitative and qualitative service aspects.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Drug-Related Problems Identified by Future Pharmacists in Medical Wards of Tertiary Hospitals in the State of Pahang, Malaysia

Elnaem¹,

Nazar²,

Rahman³

et al. 2018

JYP

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Objective: Clinical attachments undertaken by pharmacy students in Malaysia are one of the important platforms in order to prepare future candidates for patient-centred pharmacy practice. The lack of data regarding the identification of Drug-related problems (DRPs) and the suggestion of relevant interventions by final year pharmacy students has directed the current research to describe pharmacy students' abilities in identifying DRPs in their final year clinical placements. Methods: As a descriptive cross-sectional study, it involved the analysis of the clinical case reports of final year pharmacy students during their six-week clinical attachments between February and April 2017 across three different tertiary hospitals in the state of Pahang, Malaysia. A six-member team, who had received the required training by the study's principal researcher, performed the data extraction from the clinical attachment reports. Results: A total of 385 clinical case reports, identified 880 DRPs. The two most common types of identified DRPs were the untreated condition (17.4 %), followed by inappropriate drug selection (16.3 %). Nearly 47.7 % of total detected DRPs were related to the indication and efficacy domains of therapy assessment. Additionally, there was a positive correlation found between the number of underlying diseases and the number of identified DRP, r s (372) = .14, p = .007. Conclusion: During the final year clinical attachments, the majority of the students were able to identify a considerable number of DRPs in the hospital setting under the supervision of their preceptors. The characterisation of the identified DRPs could be instrumental in refining the experiential clinical learning among future pharmacy practitioners.

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Characterisation of Drug-Related Problems and Associated Factors at a Clinical Pharmacist Service-Naïve Hospital in Northern Sweden

Cited by 53 publications

References 34 publications

Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia

Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia

Daily Medication Management and Adherence in the Polymedicated Elderly: A Cross-Sectional Study in Portugal

Analysis of Drug-Related Problems Identified by Future Pharmacists in Medical Wards of Tertiary Hospitals in the State of Pahang, Malaysia

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