Characterisation of a Bioactive SiO2-CaO-CaF2-Na2O Glass Used in Composites

Sol-gel synthesis of lithium doped mesoporous bioactive glass nanoparticles and tricalcium silicate for restorative dentistry: Comparative investigation of physico-chemical structure, antibacterial susceptibility and biocompatibility

“…Overall, there were some changes to the pH and bioactivity behavior based on the particle type and the presence of Li ion. The association between pH changes of immersion media and apatite formation has been reported in multiple studies (Cerruti et al, 2005;Björkvik et al, 2016;Arango-Ospina et al, 2019;Khalid et al, 2021). This validates the approach of the present study in which pH and bioactivity in AS, HBSS and SBF are compared and contrasted in order to provide more robust data regarding the properties of these particles in relation to this important chemo-biological parameter.…”

“…Similar apatite forming ability associated with AS is also reported in a study of sol-gel derived bioactive glass approximating tooth discs ( Curtis et al, 2010 ). Although referencing melt-quench glasses, the fact that apatite could form in AS of pH four was surprising but is probably a factor of the Na and F presence in the said glass that favored pH increment and subsequent fluorapatite formation ( Khalid et al, 2021 ). The contradictory results from the different studies we cite strengthen the rationale for the importance of both broad and specific evaluations of different bioactive particles and immersion fluids in order to obtain comprehensive data on different bioactive particles.…”

“…This behaviour can be the result of the BAG chemistry and pH of the AS used. For example, significant apatite formation by a SiO 2 -CaO-CaF 2 -Na 2 O glass in AS has been reported elsewhere as early as 3 days (Khalid et al, 2021). Admittedly, the artificial saliva used was high in orthophosphates, which is known to contain 0.68 g/L of KH 2 PO 4 and 0.856 g/L of Na 2 HPO4•12H 2 O 0.856 (Tamburrino et al, 2020).…”

Ion release and hydroxyapatite precipitation of resin composites functionalized with two types of bioactive glass

“…LAS and AS were selected as immersion media because the former was used in a previous study on the protective effects of restorative materials under low-pH conditions [21], whereas the latter mimics ion concentrations and pH of the oral environment. Ion release from BG-containing composites is known to increase under acidic conditions due to faster BG dissolution [17,24], whereas in neutral and alkaline solutions, Ca and PO4 ions can be precipitated as apatite [18,25]. In the present study, AS favored precipitation over dissolution, leading to the uptake of Ca and PO4 from the solution and thereby "negative" ion release identified for all materials, even for the control (inert) composite.…”

Comparative Evaluation of Bond Strength and Microleakage of Three Ion-Releasing Restorative Materials at Various pH Levels

“…Recently, a new 'alkasite' restorative material was introduced, comprising an alkaline filler, which releases acid neutralizing ions along with fluorides, calcium and hydroxide ions along changes of the oral environment [7]. Alkaline glass fillers were shown to be able to raise the pH and form fluorapatite in media containing phosphate, which could explain the low incidence of secondary caries in alkasite restorations [8]. Ion release from fillers has been reported to induce the remineralization of dental hard tissues in previous studies [9].…”