Chapter 9. Newest approaches to singlet oxygen photosensitisation in biological media

Using photochemistry to understand and control the production of reactive oxygen species in biological environments

“…4) ever reported for MNP-photosensitizer systems. [75] Interestingly, systems where Rose Bengal was conjugated onto the surface of pure silica nanoparticle exhibit an inhibition of 1 O 2 generation, which clearly demonstrates the advantages of exploiting a plasmonic antenna to boost 1 O 2 generation. [139] …”

“…This feature article will only cover some of these new techniques, and we recommend the readers to other reviews recently published for a wider view on 1 O 2 photosensitization in biological media. [75,77] …”

“…[133] However, metal enhanced 1 O 2 generation on solid support, such as silver island films, limits the potential for bio related applications, such as the delivery of 1 O 2 at a specific location in cells. [75] Therefore, much attention has been given to MNPs-photosensitizers systems in solution. For example, a 1.8-fold increase in 1 O 2 generation was reported for aqueous solutions of riboflavin mixed with suspensions of pectin-coated Ag NPs.…”

“…Because this field is so extensive, we strongly recommend the following detailed reviews to the interested readers. [73][74][75][76][77] …”

Tuning the local solvent composition at a drug carrier surface: the effect of dimethyl sulfoxide/water mixture on the photofunctional properties of hypericin–β-lactoglobulin complexes

“…St. John's wort). 7 Hyp has proved to be efficient as an antibacterial, 8-10 antiviral 11 and antifungal 19 photodynamic agent. When dissolved in organic solvents, Hyp is endowed with a good quantum yield of fluorescence emission (F F = 0.35 AE 0.02 in dimethyl sulfoxide (DMSO) 12 ) and singlet oxygen sensitization (F D = 0.32 in ethanol, 13 0.39 AE 0.01 in methanol 14 ) upon excitation with visible light.…”